Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LAP3 | P28838 | 4/20 | 0.44 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | PPARD | Q03181 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | METAP1 | P53582 | 2/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.39 |
| ▸ | TP53 | P04637 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.37 |
| ▸ | ANPEP | P15144 | 3/20 | 0.37 |
| ▸ | ERAP1 | Q9NZ08 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3405218 | 0.82 | LAP3 (0.44) | LAP3TSHRPPARDALDH1A1METAP1 | |
| SCHEMBL27615314 | 0.79 | — | — | |
| Hydrochloric Acid SCHEMBL11048279 | 0.77 | TSHR (0.40) | LAP3TSHRPPARDALDH1A1METAP1 | |
| SCHEMBL28588887 | 0.77 | ANPEP (0.41) | LAP3ALDH1A1ANPEPERAP1 | |
| SCHEMBL11598870 | 0.74 | TSHR (0.42) | LAP3TSHRPPARDALDH1A1METAP1 | |
| SCHEMBL9775316 | 0.74 | FDPS (0.41) | LAP3TSHRPPARDTDP1TP53 | |
| SCHEMBL8069890 | 0.73 | — | — | |
| SCHEMBL10859409 | 0.73 | TSHR (0.40) | LAP3TSHRPPARDTDP1TP53 | |
| Ammonia Solution, Strong SCHEMBL10858881 | 0.73 | TSHR (0.40) | LAP3TSHRPPARDTDP1TP53 | |
| SCHEMBL12876257 | 0.73 | TSHR (0.40) | LAP3TSHRPPARDALDH1A1METAP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2012032093-A1 | TRIPODAL BISPHOSPHONATE DERIVATIVES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |
| WO-2012032089-A1 | SYNTHESIS OF TRIPODAL BISPHOSPHONATE DERIVATIVES HAVING AN ADAMANTYL BASIC FRAMEWORK FOR FUNCTIONALIZING SURFACES | JUSTUS-LIEBIG-UNIVERSITÄT GIESSEN (DE) | 2012-03-15 | — | — | WO | disclosed |