SCHEMBL4579229

SCHEMBL4579229

c1ccc(C2=C(c3ccccc3-c3ccc(-c4ccc(N(c5ccccc5)c5ccccc5)cc4)cc3)N2)cc1

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 6/20 0.38
L3MBTL1 Q9Y468 2/20 0.38
KDM4E B2RXH2 1/20 0.38
CYP1A2 P05177 1/20 0.38
CYP3A4 P08684 1/20 0.38
CYP2D6 P10635 1/20 0.38
MAPT P10636 1/20 0.38
CYP2C9 P11712 1/20 0.38
CYP2C19 P33261 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
CRHBP P24387 1/20 0.37
ATM Q13315 1/20 0.37
CRHR2 Q13324 1/20 0.37
TLR9 Q9NR96 1/20 0.37
HSD17B10 Q99714 2/20 0.35
NISCH Q9Y2I1 1/20 0.34
PTGS2 P35354 1/20 0.33
APP P05067 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4581858 0.98 ALDH1A1 (0.39) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL4581526 0.87 HSD17B1 (0.36) ALDH1A1L3MBTL1MAPTTDP1MEN1
SCHEMBL4578605 0.85 HSD17B1 (0.35) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL19998686 0.85 ALDH1A1 (0.50) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL19998693 0.85 ALDH1A1 (0.50) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL16305464 0.85 ALDH1A1 (0.50) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL17811567 0.85 ALDH1A1 (0.50) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL16385589 0.85 ALDH1A1 (0.50) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4
SCHEMBL4580148 0.85 ALDH1A1 (0.46) ALDH1A1TDP1HSD17B10NISCHPTGS2
SCHEMBL24313408 0.83 ALDH1A1 (0.48) ALDH1A1L3MBTL1KDM4ECYP1A2CYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396599-B2 Binuclear organometallic complexes and organic electroluminescent display device using the same SAMSUNG SDI CO., LTD. (KR) 2008-07-08 US disclosed