SCHEMBL4580148

SCHEMBL4580148

c1ccc(C2=C(c3ccccc3-c3ccc(-c4ccccc4C4=C(c5ccccc5)N4)cc3)N2)cc1

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 5/20 0.46
HSD17B10 Q99714 2/20 0.46
PTGS2 P35354 1/20 0.42
HPGD P15428 1/20 0.41
BCL2L1 Q07817 1/20 0.41
CYP2A6 P11509 1/20 0.41
MAPK1 P28482 1/20 0.41
DCUN1D1 Q96GG9 2/20 0.38
NISCH Q9Y2I1 1/20 0.38
CASP3 P42574 1/20 0.38
SENP8 Q96LD8 1/20 0.38
SENP7 Q9BQF6 1/20 0.38
SENP6 Q9GZR1 1/20 0.38
BACE1 P56817 1/20 0.37
DPP4 P27487 1/20 0.37
DCUN1D2 Q6PH85 1/20 0.36
FLT3 P36888 2/20 0.36
ABL1 P00519 1/20 0.35
ABCB1 P08183 1/20 0.35
BCR P11274 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4581858 0.87 ALDH1A1 (0.39) ALDH1A1HSD17B10PTGS2HPGDBCL2L1
SCHEMBL4579229 0.85 ALDH1A1 (0.38) ALDH1A1HSD17B10PTGS2HPGDBCL2L1
SCHEMBL444478 0.82 ALDH1A1 (0.53) ALDH1A1HSD17B10HPGDBCL2L1MAPK1
Hydrochloric Acid SCHEMBL7107009 0.79 ALDH1A1 (0.50) ALDH1A1HSD17B10HPGDBCL2L1MAPK1
SCHEMBL4581231 0.78 IMPDH2 (0.41) ALDH1A1HSD17B10HPGDMAPK1
SCHEMBL30257106 0.76 ALDH1A1 (0.64) ALDH1A1HSD17B10PTGS2HPGDBCL2L1
SCHEMBL6754212 0.76 ALDH1A1 (0.55) ALDH1A1HSD17B10PTGS2HPGDBCL2L1
Tannin Pyrogallol SCHEMBL13685561 0.76 ALDH1A1 (0.64) ALDH1A1HSD17B10PTGS2HPGDBCL2L1
SCHEMBL5951150 0.76 ALDH1A1 (0.64) ALDH1A1HSD17B10PTGS2HPGDBCL2L1
SCHEMBL30516212 0.76 ALDH1A1 (0.64) ALDH1A1HSD17B10PTGS2HPGDBCL2L1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396599-B2 Binuclear organometallic complexes and organic electroluminescent display device using the same SAMSUNG SDI CO., LTD. (KR) 2008-07-08 US disclosed