Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HIF1A | Q16665 | 3/20 | 0.78 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.78 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.65 |
| ▸ | MEN1 | O00255 | 2/20 | 0.65 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.65 |
| ▸ | THRB | P10828 | 1/20 | 0.65 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.65 |
| ▸ | SUMO2 | P61956 | 1/20 | 0.55 |
| ▸ | SUMO1 | P63165 | 1/20 | 0.55 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.55 |
| ▸ | SENP3 | Q9H4L4 | 1/20 | 0.55 |
| ▸ | SENP2 | Q9HC62 | 1/20 | 0.55 |
| ▸ | SENP1 | Q9P0U3 | 1/20 | 0.55 |
| ▸ | ENPP2 | Q13822 | 8/20 | 0.54 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.52 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | PTPRA | P18433 | 1/20 | 0.47 |
| ▸ | PTPRB | P23467 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10622991 | 0.89 | HIF1A (0.98) | HIF1AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL8947352 | 0.88 | ALDH1A1 (0.73) | HIF1AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL8816124 | 0.87 | HIF1A (1.00) | HIF1AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL6846279 | 0.87 | HIF1A (1.00) | HIF1AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL4068193 | 0.87 | HIF1A (1.00) | HIF1AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL1259518 | 0.86 | CYP1A2 (0.74) | HIF1AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL30655205 | 0.86 | HIF1A (0.78) | HIF1AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL592666 | 0.85 | HIF1A (0.69) | HIF1AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL15424214 | 0.84 | CYP1A2 (0.68) | HIF1AALDH1A1CYP1A2MEN1KMT2A | |
| SCHEMBL14418524 | 0.84 | ALDH1A1 (0.74) | HIF1AALDH1A1CYP1A2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-2008045055-A | MATERIAL HAVING POLYROTAXANE WHICH BRINGS ABOUT HIGH DIFFUSION COEFFICIENT | UNIV OF TOKYO | 2008-02-28 | — | — | JP | disclosed |
| WO-2008020618-A1 | POLYROTAXANE-CONTAINING MATERIAL EXERTING HIGH DIFFUSION COEFFICIENT | THE UNIVERSITY OF TOKYO (JP) | 2008-02-21 | — | — | WO | disclosed |