SCHEMBL4579460

SCHEMBL4579460

O=c1cc(Nc2ccccc2)[nH]n1-c1c(Cl)cc(Cl)cc1Cl

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 6/20 0.38
KMT2A Q03164 6/20 0.38
GSK3B P49841 4/20 0.38
STK10 O94804 2/20 0.38
SLK Q9H2G2 2/20 0.38
CHEK1 O14757 1/20 0.37
AURKA O14965 1/20 0.37
PIM1 P11309 1/20 0.37
MAPT P10636 6/20 0.37
ALDH1A1 P00352 5/20 0.37
KDM4E B2RXH2 3/20 0.37
SMN1; SMN2 Q16637 3/20 0.37
HPGD P15428 2/20 0.37
APAF1 O14727 1/20 0.37
THRB P10828 1/20 0.37
CDC25B P30305 1/20 0.37
CASP3 P42574 1/20 0.37
RECQL P46063 1/20 0.37
GALK1 P51570 1/20 0.37
UBE2I P63279 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11841834 0.85 GAA (0.40) MEN1KMT2AGSK3BSTK10SLK
SCHEMBL8409869 0.85 GSK3B (0.39) MEN1KMT2AGSK3BSTK10SLK
SCHEMBL11283689 0.82 MERTK (0.39) MEN1KMT2AGSK3BSTK10SLK
SCHEMBL10431603 0.81 PIK3CA (0.41) MEN1KMT2AGSK3BCHEK1PIM1
SCHEMBL11866741 0.81 CCNB2 (0.41) MEN1KMT2AMAPTALDH1A1SMN1; SMN2
SCHEMBL10607174 0.81 GSK3A (0.44) MEN1KMT2AGSK3BMAPTALDH1A1
SCHEMBL8909512 0.81 ALKBH5 (0.54) MEN1KMT2AGSK3BMAPTALDH1A1
SCHEMBL7039254 0.80 MAPT (0.50) MEN1KMT2AGSK3BCHEK1AURKA
SCHEMBL11807273 0.79 MAP2K1 (0.39) ALDH1A1KDM4EHPGDALKBH5MAPK1
SCHEMBL4591297 0.78 NPC1 (0.44) MEN1KMT2AKDM4EPOLBNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 191 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5407777-A Diazo-type recording material comprising a 1-phenyl-3-pyrazolidone(phenidone) as an anti-oxidant FUJI PHOTO FILM CO., LTD. (JP) 1995-04-18 US claimed
US-5328796-A Diazo type recording material utilizing microencapsulated diazo compound, a coupler and a hydroxyphenylsulfone derivative FUJI PHOTO FILM CO., LTD. (JP) 1994-07-12 US claimed
US-4686547-A DIAZO COMPOUND, POLYVINYL ALCOHOL CONTAINING SILICON, SILICA FUJI PHOTO FILM CO., LTD. (JP) 1987-08-11 US claimed
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
EP-1510246-B1 Method and apparatus for emulsification FUJIFILM CORP (JP) 2008-04-16 EP disclosed
US-7300738-B2 Azolinyl acetic acid derivative and azolinyl acetic acid derivative containing recording material FUJIFILM CORPORATION (JP) 2007-11-27 US disclosed
US-7270928-B2 Isocyanate composition, microcapsule and production method thereof, and recording material FUJIFILM CORPORATION (JP) 2007-09-18 US disclosed
US-7220529-B2 Photopolymerizable composition and recording material using the same FUJIFILM CORPORATION (JP) 2007-05-22 US disclosed
US-7205083-B2 Recording material FUJIFILM CORPORATION (JP) 2007-04-17 US disclosed
EP-1382385-B1 Microcapsule and process for manufacturing the same FUJIFILM CORP (JP) 2007-03-21 EP disclosed
US-4721700-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1988-01-26 US disclosed
US-4686547-A DIAZO COMPOUND, POLYVINYL ALCOHOL CONTAINING SILICON, SILICA FUJI PHOTO FILM CO., LTD. (JP) 1987-08-11 US disclosed
US-4665411-A MICROENCAPSULATED DIAZO COMPOUND AND COUPLER, DIELECTRIC SOLVENT FUJI PHOTO FILM CO., LTD. (JP) 1987-05-12 US disclosed
EP-0109838-B1 LIGHT AND HEAT-SENSITIVE RECORDING MATERIAL FUJI PHOTO FILM CO., LTD. (JP) 1987-04-08 EP disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 US disclosed
US-4598035-A LEUCO AND DISAZO DYES FUJI PHOTO FILM CO., LTD. (JP) 1986-07-01 US disclosed
US-4529681-A Microcapsules containing vinyl compound, photoinitiator and color forming compound FUJI PHOTO FILM CO., LTD. (JP) 1985-07-16 US disclosed
EP-0123224-A2 Heat sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1984-10-31 EP disclosed
EP-0109838-A2 Light and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1984-05-30 EP disclosed