SCHEMBL4591297

SCHEMBL4591297

O=C(Nc1cc(=O)n(-c2c(Cl)cc(Cl)cc2Cl)[nH]1)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
NPC1 O15118 3/20 0.44
RAB9A P51151 3/20 0.44
MEN1 O00255 1/20 0.42
PABPC1 P11940 1/20 0.42
CCR6 P51684 1/20 0.42
KMT2A Q03164 1/20 0.42
ATM Q13315 1/20 0.42
HKDC1 Q2TB90 1/20 0.42
KDM4E B2RXH2 1/20 0.42
NPSR1 Q6W5P4 1/20 0.42
RXFP1 Q9HBX9 1/20 0.42
KCNK3 O14649 2/20 0.42
KCNK9 Q9NPC2 2/20 0.42
KCNMA1 Q12791 1/20 0.42
CA12 O43570 1/20 0.40
CA9 Q16790 1/20 0.40
PSD A5PKW4 1/20 0.40
HDAC1 Q13547 1/20 0.40
HDAC8 Q9BY41 1/20 0.40
HDAC6 Q9UBN7 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL11685836 0.87 MEN1 (0.41) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL10396769 0.87 SMN1; SMN2 (0.51) MEN1KMT2AKDM4ENPSR1HDAC1
SCHEMBL9727104 0.87 P2RX1 (0.50) NPC1RAB9AMEN1KMT2ARXFP1
SCHEMBL7626297 0.82 TSHR (0.48) MEN1PABPC1CCR6KMT2AATM
SCHEMBL11859198 0.79 MEN1 (0.44) NPC1MEN1KMT2ATDP1
SCHEMBL4579460 0.78 MEN1 (0.38) NPC1RAB9AMEN1KMT2AATM
SCHEMBL5637633 0.78 NPC1 (0.40) NPC1RAB9AMEN1PABPC1CCR6
SCHEMBL11477480 0.76 HTT (0.38) NPC1RAB9AMEN1KMT2AKDM4E
SCHEMBL10614357 0.73 NPC1 (0.41) NPC1RAB9AKDM4EPOLBTDP1
SCHEMBL5636397 0.72 MAPT (0.39) NPC1RAB9AMEN1KMT2AKDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 170 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5328796-A Diazo type recording material utilizing microencapsulated diazo compound, a coupler and a hydroxyphenylsulfone derivative FUJI PHOTO FILM CO., LTD. (JP) 1994-07-12 US claimed
EP-1298490-B1 Photopolymerizable composition and recording material FUJIFILM CORP (JP) 2008-08-13 EP disclosed
US-7399569-B2 Method for producing microcapsules, microcapsules, recording material, and heat-sensitive recording material FUJIFILM CORPORATION (JP) 2008-07-15 US disclosed
EP-1510246-B1 Method and apparatus for emulsification FUJIFILM CORP (JP) 2008-04-16 EP disclosed
US-7270928-B2 Isocyanate composition, microcapsule and production method thereof, and recording material FUJIFILM CORPORATION (JP) 2007-09-18 US disclosed
US-7220529-B2 Photopolymerizable composition and recording material using the same FUJIFILM CORPORATION (JP) 2007-05-22 US disclosed
US-7205083-B2 Recording material FUJIFILM CORPORATION (JP) 2007-04-17 US disclosed
EP-1382385-B1 Microcapsule and process for manufacturing the same FUJIFILM CORP (JP) 2007-03-21 EP disclosed
US-20070048666-A1 Two-photon recording method, two-photon absorption recording material, two-photon absorption recording-reproduction method and optical recoding medium FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-20070047038-A1 Hologram recording method, hologram recording material, optical recording medium FUJI PHOTO FILM CO., LTD. 2007-03-01 US disclosed
US-4644376-A Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1987-02-17 US disclosed
US-4598035-A LEUCO AND DISAZO DYES FUJI PHOTO FILM CO., LTD. (JP) 1986-07-01 US disclosed
US-4529681-A Microcapsules containing vinyl compound, photoinitiator and color forming compound FUJI PHOTO FILM CO., LTD. (JP) 1985-07-16 US disclosed
EP-0123224-A2 Heat sensitive recording materials FUJI PHOTO FILM CO., LTD. (JP) 1984-10-31 EP disclosed
EP-0109838-A2 Light and heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1984-05-30 EP disclosed
US-4258127-A PHOTOGRAPHY, FOGGING FUJI PHOTO FILM CO., LTD. (JP) 1981-03-24 US disclosed
US-3997348-A FERRIC SALT BLEACHING SOLUTION FUJI PHOTO FILM CO., LTD. (JA) 1976-12-14 US disclosed
US-3984249-A TREATING WITH HYDROGEN EASTMAN KODAK COMPANY (US) 1976-10-05 US disclosed
US-RE28760-E Photographic element including superimposed silver halide layers of different speeds EASTMAN KODAK COMPANY (US) 1976-04-06 US disclosed
US-3948659-A BLEACHING FUJI PHOTO FILM CO., LTD. (JA) 1976-04-06 US disclosed