Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCL8 | P10145 | 7/20 | 0.51 |
| ▸ | PTGS2 | P35354 | 5/20 | 0.50 |
| ▸ | TTR | P02766 | 3/20 | 0.50 |
| ▸ | PTGS1 | P23219 | 3/20 | 0.50 |
| ▸ | AKR1B10 | O60218 | 1/20 | 0.50 |
| ▸ | UGT1A9 | O60656 | 1/20 | 0.50 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.50 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.50 |
| ▸ | MT-CO2 | P00403 | 1/20 | 0.50 |
| ▸ | ALB | P02768 | 1/20 | 0.50 |
| ▸ | UGT1A6 | P19224 | 1/20 | 0.50 |
| ▸ | UGT1A1 | P22309 | 1/20 | 0.50 |
| ▸ | CXCR1 | P25024 | 1/20 | 0.50 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.50 |
| ▸ | AGTR2 | P50052 | 1/20 | 0.50 |
| ▸ | NR1I3 | Q14994 | 1/20 | 0.50 |
| ▸ | SLC22A6 | Q4U2R8 | 1/20 | 0.50 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.50 |
| ▸ | UGT1A7 | Q9HAW7 | 1/20 | 0.50 |
| ▸ | UGT1A10 | Q9HAW8 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9618521 | 0.98 | CXCL8 (0.50) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL8053100 | 0.98 | CXCL8 (0.50) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL29598223 | 0.98 | CXCL8 (0.50) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL9618518 | 0.98 | CXCL8 (0.50) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| Potassium SCHEMBL8053105 | 0.98 | CXCL8 (0.50) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| Rubidium SCHEMBL9618522 | 0.98 | CXCL8 (0.50) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL1961600 | 0.98 | CXCL8 (0.50) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| Diethylamine SCHEMBL9790067 | 0.92 | CXCL8 (0.47) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL10412874 | 0.91 | CXCL8 (0.50) | CXCL8PTGS2TTRPTGS1AKR1B10 | |
| SCHEMBL10413114 | 0.91 | CXCL8 (0.50) | CXCL8PTGS2TTRPTGS1AKR1B10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 185 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2170826-B1 | PRO-DRUGS OF NSAIAS WITH VERY HIGH SKIN AND MEMBRANES PENETRATION RATES AND THEIR NEW MEDICINAL USES | TECHFIELDS INC (US) | 2022-04-27 | — | — | EP | claimed |
| EP-2598475-A1 | PROCESS FOR THE SYNTHESIS OF DICLOFENAC CHOLINE SALT | FARMAKA S.r.l. (IT) | 2013-06-05 | — | — | EP | claimed |
| WO-2013008104-A1 | PROCESS FOR THE SYNTHESIS OF DICLOFENAC CHOLINE SALT | FARMAKA S.R.L. (IT) | 2013-01-17 | — | — | WO | claimed |
| US-8153689-B2 | Pleuromutilin derivatives for the treatment of diseases mediated by microbes | NABRIVA THERAPEUTICS AG (AT) | 2012-04-10 | — | — | US | claimed |
| US-20120029072-A1 | PLEUROMUTILIN DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY MICROBES | NABRIVA THERAPEUTICS AG | 2012-02-02 | — | — | US | claimed |
| CN-1747731-A | Imidazopyridines containing combinations and their use in treating gastrointestinal inflammatory disorders | ALTANA PHARMA AG (DE) | 2006-03-15 | — | — | CN | claimed |
| EP-0946170-B1 | DICLOFENAC FOR THE TREATMENT OF VASCULOPATHIES | EXOCELL INC (US) | 2005-10-12 | — | — | EP | claimed |
| CN-1625411-A | Combination of a NSAID and a PDE-4 inhibitor | ALTANA PHARMA AG (DE) | 2005-06-08 | — | — | CN | claimed |
| US-6710086-B1 | CHEMICALLY MODIFIED PHARMACOLOGICALLY ACTIVE AGENT IN CARRIER; REDUCE THE DAMAGE TO THE GASTROINTESTINAL TRACT | MEDINOX, INC. | 2004-03-23 | — | — | US | claimed |
| WO-2003068203-A1 | USE OF A COMBINATION OF A NON-STEROIDAL ANTI-INFLAMMATORY AGENT AND GUAIFENESIN FOR THE TREATMENT OF ACUTE PAIN | ZENTIVA, A.S. (CZ) | 2003-08-21 | — | — | WO | claimed |
| JP-4312561-A | — | — | None | — | — | JP | disclosed |
| JP-55013227-A | — | — | None | — | — | JP | disclosed |
| JP-4091061-A | — | — | None | — | — | JP | disclosed |
| JP-54145627-A | — | — | None | — | — | JP | disclosed |
| JP-63041475-A | — | — | None | — | — | JP | disclosed |
| EP-0041576-A1 | 1-(2,6-DICHLOROPHENYL)-2-QUINOLINONEIMINE-3-CARBOXYLIC ACID, PRODUCTION PROCESS THEREFOR AND ANTI-INFLAMMATORY AND ANALGESIC COMPOSITION CONTAINING THE COMPOUND | DAITO KOEKI KABUSHIKI KAISHA (JP) | 1981-12-16 | — | — | EP | disclosed |
| US-4189595-A | [N-benzyl-o-(2,6-dichloroanilino)phenyl]acetic acid derivatives | NISSAN CHEMICAL INDUSTRIES, LTD. (JP) | 1980-02-19 | — | — | US | disclosed |
| JP-S5522628-A | GLYCIDATE AND ITS PREPARATION | DAITO KOEKI KK | 1980-02-18 | — | — | JP | disclosed |
| JP-S5513227-A | PRODUCTION OF 2-(2,6-DICHLOROANILINO)PHENYL ACETIC ACID | IKEDA MOHANDOU:KK | 1980-01-30 | — | — | JP | disclosed |
| JP-S54145627-A | PREPARATION OF 2-(2,6-DICHLOROANILINO)PHENYL ACETIC ACID | NISSAN CHEM IND LTD | 1979-11-14 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120029072-A1 | PLEUROMUTILIN DERIVATIVES FOR THE TREATMENT OF DISEASES MEDIATED BY MICROBES | FABP2, FABP6, PLEC | CXCL8 357/4885PTGS2 407/4885TTR 32/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.