SCHEMBL458017

SCHEMBL458017

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nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
PDE4A P27815 1/20 0.43
USP2 O75604 1/20 0.40
SLCO1B1 Q9Y6L6 1/20 0.40
AKR1B1 P15121 1/20 0.40
KDM4E B2RXH2 2/20 0.38
TOP1 P11387 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7172534 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL38895 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL31150922 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL2315458 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL29754090 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL23067650 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL38896 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL29355171 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL260109 0.93 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL187021 0.93 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 79 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12583881-B2 Device and cassette for performing a plurality of synthesis processes of preparing a radiopharmaceutical in series OUT AND OUT CHEMISTRY S.P.R.L. (BE) 2026-03-24 US claimed
US-20250049409-A1 METHODS OF QUANTIFYING SKELETAL MUSCLE PERFUSION USING PET IMAGING RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL 2025-02-13 US claimed
US-20240059724-A1 DEVICE AND CASSETTE FOR PERFORMING A PLURALITY OF SYNTHESIS PROCESSES OF PREPARING A RADIOPHARMACEUTICAL IN SERIES OUT AND OUT CHEMISTRY S.P.R.L. (BE) 2024-02-22 US claimed
CN-115323021-A Method for regulating antibody glycoform and application thereof 杭州奕安济世生物药业有限公司 2022-11-11 CN claimed
CN-113549667-A Method for reducing galactosylation of antibody 杭州奕安济世生物药业有限公司 2021-10-26 CN claimed
US-20090324682-A1 Medical stent provided with inhibitors of atp synthesis INTERSTITIAL THERAPEUTICS (CH) 2009-12-31 US claimed
EP-1789030-A2 MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS Interstitial Therapeutics (CH) 2007-05-30 EP claimed
EP-1789107-A2 MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS Interstitial Therapeutics (CH) 2007-05-30 EP claimed
WO-2006024488-A2 MEDICAL STENT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
WO-2006024491-A1 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CELL PROLIFERATION INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
WO-2006024490-A2 METHODS AND COMPOSITIONS FOR THE TREATMENT OF CELL PROLIFERATION INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
WO-2006024492-A2 MEDICAL IMPLANT PROVIDED WITH INHIBITORS OF ATP SYNTHESIS INTERSTITIAL THERAPEUTICS (CH) 2006-03-09 WO claimed
US-5770407-A Process for preparing nucleotide inhibitors of glycosyltransferases THE SCRIPPS RESEARCH INSTITUTE (US) 1998-06-23 US claimed
WO-1998025940-A1 INHIBITORS OF GLYCOSYLTRANSFERASES THE SCRIPPS RESEARCH INSTITUTE (US) 1998-06-18 WO claimed
US-12583881-B2 Device and cassette for performing a plurality of synthesis processes of preparing a radiopharmaceutical in series OUT AND OUT CHEMISTRY S.P.R.L. (BE) 2026-03-24 US disclosed
CN-115323021-B Method for regulating antibody glycoform and application thereof 创胜生物医药(杭州)有限公司 2025-12-05 CN disclosed
US-20250049409-A1 METHODS OF QUANTIFYING SKELETAL MUSCLE PERFUSION USING PET IMAGING RESEARCH INSTITUTE AT NATIONWIDE CHILDREN'S HOSPITAL 2025-02-13 US disclosed
WO-2002048320-A2 CRYSTAL STRUCTURES OF RETAINING GLYCOSYLTRANSFERASES THE UNIVERSITY OF BRITISH COLUMBIA (CA) 2002-06-20 WO disclosed
US-5770407-A Process for preparing nucleotide inhibitors of glycosyltransferases THE SCRIPPS RESEARCH INSTITUTE (US) 1998-06-23 US disclosed
WO-1998025940-A1 INHIBITORS OF GLYCOSYLTRANSFERASES THE SCRIPPS RESEARCH INSTITUTE (US) 1998-06-18 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090324682-A1 Medical stent provided with inhibitors of atp synthesis ATP5ME, ATP5F1A, ATP5MG LMNA 4786/4885L3MBTL1 3926/4885TDP1 3298/4885
US-12583881-B2 Device and cassette for performing a plurality of synthesis processes of preparing a radiopharmaceutical in series TMEM14C, FLT1, SLC6A12 LMNA 2083/4885L3MBTL1 3757/4885TDP1 1176/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.