SCHEMBL38896

SCHEMBL38896

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nearest known ligand 0.52

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.52
L3MBTL1 Q9Y468 1/20 0.52
TDP1 Q9NUW8 1/20 0.50
PDE4A P27815 1/20 0.43
USP2 O75604 1/20 0.40
SLCO1B1 Q9Y6L6 1/20 0.40
AKR1B1 P15121 1/20 0.40
KDM4E B2RXH2 2/20 0.38
TOP1 P11387 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7172534 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL38895 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL31150922 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL458017 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL2315458 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL29754090 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL23067650 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL29355171 1.00 LMNA (0.52) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL260109 0.93 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2
SCHEMBL187021 0.93 LMNA (0.48) LMNAL3MBTL1TDP1PDE4AUSP2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1173 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20250258147-A1 Radiopharmaceutical Production System and Quality Control System Utilizing High Performance Liquid Chromatography BEST ABT, INC. (US) 2025-08-14 US claimed
EP-4590346-A1 FIBROBLAST ACTIVATION PROTEIN (FAP) INHIBITORS, FAP CONJUGATES, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF Nuclidium AG (CH) 2025-07-30 EP claimed
EP-4582080-A1 DISPENSER FOR MUCOSAL ADMINISTRATION COMPRISING 2-DEOXY-GLUCOSE OR ANALOGUES THEREOF G.ST Antivirals GmbH (AT) 2025-07-09 EP claimed
US-20250114386-A1 COMBINATION OF A GLYCOSYLATION INHIBITOR WITH ONE CAR CELL THERAPY FOR TREATING CANCER OSPEDALE SAN RAFFAELE S.R.L. (IT) 2025-04-10 US claimed
WO-2025042868-A1 COMBINATIONS OF HETEROAROTINOIDS AND GLYCOLYTIC INHIBITORS FOR USE AS CANCER TREATMENTS THE BOARD OF REGENTS OF THE UNIVERSITY OF OKLAHOMA (US) 2025-02-27 WO claimed
US-12235250-B2 Radiopharmaceutical production system and quality control system utilizing high performance liquid chromatography BEST ABT, INC. (US) 2025-02-25 US claimed
US-20250017950-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL BUSINESS LTD (GB) 2025-01-16 US claimed
US-20240316083-A1 MEDICAMENT FOR PREVENTION OR TREATMENT OF RHINOVIRUS INFECTION MEDIZINISCHE UNIVERSITAT WIEN (AT) 2024-09-26 US claimed
EP-4433077-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS UCL Business Ltd (GB) 2024-09-25 EP claimed
WO-2024064968-A1 FIBROBLAST ACTIVATION PROTEIN (FAP) INHIBITORS, FAP CONJUGATES, AND DIAGNOSTIC AND THERAPEUTIC USES THEREOF NUCLIDIUM AG (CH) 2024-03-28 WO claimed
WO-1997002046-A2 SACCHARIDE CONJUGATES Deutsches Krebsforschungszentrum Stiftung des öffentlichen Rechts (DE) 1997-01-23 WO claimed
EP-0641350-A4 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE. GEN ELECTRIC (US) 1995-08-23 EP claimed
EP-0641350-A1 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE GENERAL ELECTRIC COMPANY (US) 1995-03-08 EP claimed
WO-1994021653-A1 METHOD FOR MAKING 2-FLUORO-2-DEOXYGLUCOSE GENERAL ELECTRIC COMPANY (US) 1994-09-29 WO claimed
US-5057301-A MODIFIED CELLULAR SUBSTRATES USED AS LINKERS FOR INCREASED CELL RETENTION OF DIAGNOSTIC AND THERAPEUTIC AGENTS NEORX CORPORATION (US) 1991-10-15 US claimed
EP-0222425-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-05-20 EP claimed
EP-0221588-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-05-13 EP claimed
EP-0218300-A2 Brain-specific drug delivery UNIVERSITY OF FLORIDA (US) 1987-04-15 EP claimed
EP-0110955-A1 BRAIN-SPECIFIC DRUG DELIVERY. UNIV FLORIDA (US) 1984-06-20 EP claimed
WO-1983003968-A1 BRAIN-SPECIFIC DRUG DELIVERY UNIVERSITY OF FLORIDA (US) 1983-11-24 WO claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20250114386-A1 COMBINATION OF A GLYCOSYLATION INHIBITOR WITH ONE CAR CELL THERAPY FOR TREATING CANCER ST6GAL1, ENGASE, MAN2A1 LMNA 4034/4885L3MBTL1 2426/4885TDP1 1832/4885
US-20240316083-A1 MEDICAMENT FOR PREVENTION OR TREATMENT OF RHINOVIRUS INFECTION SORD, MME, DERA LMNA 3911/4885L3MBTL1 2484/4885TDP1 4535/4885
US-20250017950-A1 COMPOUNDS FOR TREATING MITOCHONDRIAL DNA DISORDERS POLRMT, TK2, GOT2 LMNA 2348/4885L3MBTL1 518/4885TDP1 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.