Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX15 | P16050 | 1/20 | 0.67 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.53 |
| ▸ | MEN1 | O00255 | 3/20 | 0.53 |
| ▸ | ALPL | P05186 | 1/20 | 0.53 |
| ▸ | ALPI | P09923 | 1/20 | 0.53 |
| ▸ | ALPG | P10696 | 1/20 | 0.53 |
| ▸ | FFAR1 | O14842 | 4/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.49 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.49 |
| ▸ | PLA2G4B | P0C869 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | FFAR4 | Q5NUL3 | 2/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3898377 | 0.85 | ALOX15 (0.74) | ALOX15KMT2AMEN1ALPLALPI | |
| SCHEMBL9824596 | 0.82 | ALOX15 (0.69) | ALOX15KMT2AMEN1ALPLALPI | |
| SCHEMBL15396047 | 0.81 | ALOX15 (0.68) | ALOX15KMT2AMEN1ALPLALPI | |
| SCHEMBL25364295 | 0.81 | FFAR1 (0.54) | ALOX15FFAR1ALDH1A1GAACYP2C19 | |
| SCHEMBL10603024 | 0.81 | FFAR1 (0.57) | ALOX15KMT2AMEN1FFAR1GAA | |
| SCHEMBL8127 | 0.81 | ALOX15 (1.00) | ALOX15KMT2AMEN1ALPLALPI | |
| SCHEMBL1318870 | 0.81 | ALOX15 (1.00) | ALOX15KMT2AMEN1ALPLALPI | |
| SCHEMBL13472198 | 0.79 | KMT2A (0.57) | ALOX15KMT2AMEN1ALPLALPI | |
| SCHEMBL6247942 | 0.79 | PLA2G4B (0.57) | ALOX15KMT2AMEN1ALPLALPI | |
| SCHEMBL11956755 | 0.79 | ALOX15 (0.65) | ALOX15KMT2AMEN1ALPLALPI |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8470805-B2 | Processes for preparing piperazinium salts of KMUP and use thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-06-25 | — | — | US | claimed |
| WO-2012031445-A1 | PROCESSES FOR PREPARING PIPERAZINIUM SALTS OF KMUP AND USE THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (CN) | 2012-03-15 | — | — | WO | claimed |
| US-20110136767-A1 | PROCESSES FOR PREPARING PIPERAZINIUM SALTS OF KMUP AND USE THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-06-09 | — | — | US | claimed |
| US-20100317671-A1 | XANTHINE-BASED CYCLIC GMP-ENHANCING RHO-KINASE INHIBITOR INHIBITS PHYSIOLOGICAL ACTIVITIES OF LUNG EPITHELIAL CELL LINE | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-12-16 | — | — | US | claimed |
| US-8497370-B2 | Processes for preparing amine salts of sildenafil-analogues and use thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-07-30 | — | — | US | disclosed |
| US-8470805-B2 | Processes for preparing piperazinium salts of KMUP and use thereof | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2013-06-25 | — | — | US | disclosed |
| US-20120108604-A1 | PROCESSES FOR PREPARING AMINE SALTS OF SILDENAFIL-ANALOGUES AND USE THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2012-05-03 | — | — | US | disclosed |
| WO-2012031445-A1 | PROCESSES FOR PREPARING PIPERAZINIUM SALTS OF KMUP AND USE THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (CN) | 2012-03-15 | — | — | WO | disclosed |
| US-20110136767-A1 | PROCESSES FOR PREPARING PIPERAZINIUM SALTS OF KMUP AND USE THEREOF | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2011-06-09 | — | — | US | disclosed |
| US-20100317671-A1 | XANTHINE-BASED CYCLIC GMP-ENHANCING RHO-KINASE INHIBITOR INHIBITS PHYSIOLOGICAL ACTIVITIES OF LUNG EPITHELIAL CELL LINE | KAOHSIUNG MEDICAL UNIVERSITY (TW) | 2010-12-16 | — | — | US | disclosed |
| US-5166167-A | Fungicides | ROUSSEL UCLAF (FR) | 1992-11-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110136767-A1 | PROCESSES FOR PREPARING PIPERAZINIUM SALTS OF KMUP AND USE THEREOF | U2SURP, RRP15, KYNU | ALOX15 2407/4885KMT2A 216/4885MEN1 309/4885 |
| US-20100317671-A1 | XANTHINE-BASED CYCLIC GMP-ENHANCING RHO-KINASE INHIBITOR INHIBITS PHYSIOLOGICAL ACTIVITIES OF LUNG EPITHELIAL CELL LINE | RHOA, PRKG1, ROCK1 | ALOX15 1402/4885KMT2A 1131/4885MEN1 3775/4885 |
| US-20120108604-A1 | PROCESSES FOR PREPARING AMINE SALTS OF SILDENAFIL-ANALOGUES AND USE THEREOF | PDE3A, PDE5A, PDE3B | ALOX15 3441/4885KMT2A 2322/4885MEN1 324/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.