Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CES1 | P23141 | 4/20 | 0.47 |
| ▸ | DAO | P14920 | 2/20 | 0.47 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.47 |
| ▸ | NSD2 | O96028 | 1/20 | 0.47 |
| ▸ | BCHE | P06276 | 1/20 | 0.47 |
| ▸ | CASP3 | P42574 | 1/20 | 0.45 |
| ▸ | CASP2 | P42575 | 1/20 | 0.45 |
| ▸ | CASP7 | P55210 | 1/20 | 0.45 |
| ▸ | CASP6 | P55212 | 1/20 | 0.45 |
| ▸ | CASP8 | Q14790 | 1/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.45 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.45 |
| ▸ | HPGD | P15428 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.45 |
| ▸ | HTT | P42858 | 1/20 | 0.45 |
| ▸ | CDK5 | Q00535 | 1/20 | 0.45 |
| ▸ | CDK5R1 | Q15078 | 1/20 | 0.45 |
| ▸ | NCOA1 | Q15788 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026300 | 1.00 | CES1 (0.47) | CES1DAODNMT1NSD2BCHE | |
| SCHEMBL31026294 | 1.00 | CES1 (0.47) | CES1DAODNMT1NSD2BCHE | |
| SCHEMBL31026293 | 1.00 | CES1 (0.47) | CES1DAODNMT1NSD2BCHE | |
| SCHEMBL3200379 | 0.78 | ALDH1A1 (0.40) | DNMT1ALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL6317220 | 0.78 | ALDH1A1 (0.40) | DNMT1ALDH1A1CYP1A2HPGDCYP2C19 | |
| SCHEMBL31531054 | 0.77 | CES1 (0.51) | CES1DAONSD2BCHECASP3 | |
| SCHEMBL21792472 | 0.75 | SIRT2 (0.37) | DAODNMT1ALDH1A1CYP1A2HPGD | |
| SCHEMBL10566907 | 0.72 | MAPT (0.53) | CES1DAONSD2BCHECYP1A2 | |
| SCHEMBL31016527 | 0.72 | MAPT (0.53) | CES1DAONSD2BCHECYP1A2 | |
| SCHEMBL57037 | 0.71 | DNMT1 (0.53) | CES1DNMT1CASP3CASP2CASP7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 41 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2387598-B1 | BLACK MATRIX FOR COLOUR FILTERS | BASF SE (DE) | 2014-06-04 | — | — | EP | disclosed |
| US-8691002-B2 | Organic black pigments and their preparation | BASF SE (DE) | 2014-04-08 | — | — | US | disclosed |
| US-8691002-B2 | Organic black pigments and their preparation | BASF SE (DE) | 2014-04-08 | — | — | US | disclosed |
| US-8669026-B2 | Black matrix for colour filters | BASF SE (DE) | 2014-03-11 | — | — | US | disclosed |
| US-8669026-B2 | Black matrix for colour filters | BASF SE (DE) | 2014-03-11 | — | — | US | disclosed |
| EP-2240175-B1 | COMPOUNDS WITH MDR1-INVERSE ACTIVITY | US GOV HEALTH & HUMAN SERV (US) | 2013-01-02 | — | — | EP | disclosed |
| WO-2012033601-A1 | THIOSEMICARBAZONES WITH MDR1 - INVERSE ACTIVITY | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH & HUMAN SERVICES (US) | 2012-03-15 | — | — | WO | disclosed |
| US-20110294385-A1 | ORGANIC BLACK PIGMENTS AND THEIR PREPARATION | BASF SE (DE) | 2011-12-01 | — | — | US | disclosed |
| US-20110294385-A1 | ORGANIC BLACK PIGMENTS AND THEIR PREPARATION | BASF SE (DE) | 2011-12-01 | — | — | US | disclosed |
| US-7994333-B2 | Methods and compositions for selectin inhibition | WYETH LLC (US) | 2011-08-09 | — | — | US | disclosed |
| EP-1326597-A2 | METHODS FOR MODULATING BLADDER FUNCTION | AMERICAN HOME PRODUCTS CORPORATION (US) | 2003-07-16 | — | — | EP | disclosed |
| WO-2002032419-A2 | METHODS FOR MODULATING BLADDER FUNCTION | WYETH (US) | 2002-04-25 | — | — | WO | disclosed |
| EP-0747354-B1 | 3-Substituted oxindole derivatives as potassium channel modulators | BRISTOL MYERS SQUIBB CO (US) | 2000-08-16 | — | — | EP | disclosed |
| US-5602169-A | USEFUL IN REDUCING NEURONAL DAMAGE DURING ISCHEMIC STROKE | BRISTOL-MYERS SQUIBB COMPANY (US) | 1997-02-11 | — | — | US | disclosed |
| EP-0747354-A1 | 3-Substituted oxindole derivatives as potassium channel modulators | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-12-11 | — | — | EP | disclosed |
| US-5565483-A | ADMINISTERING AS THERAPY FOR ISCHEMIA, CONVULSIONS OR ASTHMA | BRISTOL-MYERS SQUIBB COMPANY (US) | 1996-10-15 | — | — | US | disclosed |
| EP-0432648-B1 | Isatine derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-08-02 | — | — | EP | disclosed |
| EP-0503349-B1 | Hydrazone derivatives, their preparation and use | NEUROSEARCH AS (DK) | 1995-01-04 | — | — | EP | disclosed |
| EP-0503349-A1 | Hydrazone derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1992-09-16 | — | — | EP | disclosed |
| EP-0432648-A2 | Isatine derivatives, their preparation and use | NEUROSEARCH A/S (DK) | 1991-06-19 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110294385-A1 | ORGANIC BLACK PIGMENTS AND THEIR PREPARATION | IK, CRY1, PAH | CES1 3271/4885DAO 3741/4885DNMT1 850/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.