SCHEMBL4580780

SCHEMBL4580780

CC(=O)C(C(=O)OC(=O)C(Cc1ccccc1)(Cc1ccccc1)Cc1ccccc1)C(O)(CC(=O)O)C(=O)O

nearest known ligand 0.38

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 1/20 0.38
ALDH1A1 P00352 4/20 0.37
RECQL P46063 1/20 0.37
MMP8 P22894 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HIF1A Q16665 1/20 0.34
CTRB1 P17538 1/20 0.33
MEN1 O00255 2/20 0.33
KMT2A Q03164 2/20 0.33
LMNA P02545 2/20 0.33
KDM4E B2RXH2 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP2D6 P10635 1/20 0.33
PPARG P37231 1/20 0.32
PPARA Q07869 1/20 0.32
CPT2 P23786 1/20 0.32
ACLY P53396 1/20 0.32
AKR1B1 P15121 1/20 0.32
PTPRC P08575 1/20 0.32
PTPN1 P18031 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL4580774 0.84 TSHR (0.37) TSHRALDH1A1RECQLMMP8SMN1; SMN2
SCHEMBL5067141 0.78 ACLY (0.46) TSHRALDH1A1HIF1ACYP2D6CPT2
SCHEMBL242005 0.71 SLC13A5 (0.47) TSHRALDH1A1SMN1; SMN2HIF1AMEN1
SCHEMBL1463441 0.71 CPT2 (0.44) TSHRALDH1A1RECQLHIF1AMEN1
SCHEMBL30441388 0.70 TDP1 (0.46) TSHRALDH1A1SMN1; SMN2KMT2ALMNA
SCHEMBL11759624 0.70 CPT2 (0.43) TSHRALDH1A1RECQLHIF1AMEN1
SCHEMBL4580777 0.69 ALDH1A1 (0.35) ALDH1A1RECQLMMP8SMN1; SMN2HIF1A
SCHEMBL11759770 0.67 HSPD1 (0.42) TSHRALDH1A1RECQLHIF1AMEN1
SCHEMBL284430 0.67 ACLY (0.55) TSHRALDH1A1RECQLHIF1AMEN1
SCHEMBL28860400 0.67 ACLY (0.55) TSHRALDH1A1RECQLHIF1AMEN1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7407686-B2 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION (JP) 2008-08-05 US disclosed
US-20060062936-A1 Optical film, polarizing plate and display device utilising the film, and production method of optical film KONICA CORPORATION 2006-03-23 US disclosed
US-20030170482-A1 Optical film, polarizing plate and display device utilizing the film, and production method of optical film KONICA CORPORATION (JP) 2003-09-11 US disclosed