SCHEMBL4580833

SCHEMBL4580833

CCCCc1cccc2c1C(c1cc(C)ccc1C)C(=O)O2

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GAA P10253 2/20 0.42
MAPT P10636 3/20 0.36
MAOA P21397 1/20 0.32
HTT P42858 3/20 0.32
ALDH1A1 P00352 4/20 0.31
TSHR P16473 2/20 0.31
MAPK1 P28482 1/20 0.31
L3MBTL1 Q9Y468 1/20 0.31
GRM2 Q14416 1/20 0.31
CYP1A2 P05177 1/20 0.31
HPGD P15428 1/20 0.31
HSD17B10 Q99714 1/20 0.31
KDM4E B2RXH2 1/20 0.31
NPC1 O15118 1/20 0.31
KMT2A Q03164 1/20 0.31
PBRM1 Q86U86 1/20 0.31
NPSR1 Q6W5P4 1/20 0.31
ALDH2 P05091 1/20 0.30
CYP1A1 P04798 1/20 0.30
CNR1 P21554 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL5819204 0.83 HTR2A (0.35) GAAMAPTMAOAHTTTSHR
SCHEMBL1557118 0.82 GAA (0.33) GAAMAOACYP1A1
SCHEMBL4449574 0.78 GAA (0.42) GAAALDH1A1HPGDCYP1A1
SCHEMBL3896297 0.73 CSNK2B (0.41) GAAMAPTHSD17B10KDM4ECYP1A1
SCHEMBL3897037 0.73 CSNK2B (0.41) GAAMAPTHSD17B10KDM4ECYP1A1
SCHEMBL4445358 0.73 CSNK2B (0.39) MAPTMAOAALDH1A1TSHRL3MBTL1
O-Xylene SCHEMBL29071680 0.72 CYP1A2 (0.35) MAPTMAOAHTTALDH1A1MAPK1
SCHEMBL18554810 0.72 CTRC (0.35) MAPTALDH1A1MAPK1CYP1A2HPGD
SCHEMBL1828712 0.72 ALDH1A1 (0.40) GAAMAPTHTTALDH1A1MAPK1
SCHEMBL6674488 0.69 LMNA (0.36) MAOAALDH1A1MAPK1NPC1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20080043176-A1 Method of Manufacturing a Polarizing Plate Protective Film, Polarizing Plate Protective Film, Polarizing Plate, and Liquid Crystal Display Device KONICA MINOLTA OPTO, INC. (JP) 2008-02-21 US disclosed
US-20080013173-A1 METHOD OF MANUFACTURING A POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE PROTECTIVE FILM, POLARIZING PLATE, AND LIQUID CRYSTAL DISPLAY DEVICE KONICA MINOLTA OPTO, INC. (JP) 2008-01-17 US disclosed