Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.45 |
| ▸ | GLA | P06280 | 4/20 | 0.45 |
| ▸ | HPGD | P15428 | 3/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.45 |
| ▸ | MAOA | P21397 | 2/20 | 0.45 |
| ▸ | CASP1 | P29466 | 2/20 | 0.45 |
| ▸ | CASP7 | P55210 | 2/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.45 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.45 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.45 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.45 |
| ▸ | NQO2 | P16083 | 1/20 | 0.45 |
| ▸ | DRD1 | P21728 | 1/20 | 0.45 |
| ▸ | ACHE | P22303 | 1/20 | 0.45 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.45 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.45 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1170136 | 0.82 | GABRA1 (0.48) | ALDH1A1HPGDSMN1; SMN2MAOAHSD17B10 | |
| SCHEMBL135810 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL29548932 | 0.79 | ALDH1A1 (0.47) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL3713908 | 0.77 | ALDH1A1 (0.42) | KDM4EALDH1A1GLAHPGDMAOA | |
| SCHEMBL28193792 | 0.76 | ALDH1A1 (0.50) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL3042272 | 0.73 | KDM4E (0.64) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| Acridine SCHEMBL2317889 | 0.72 | ALDH1A1 (0.52) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL2066411 | 0.71 | KDM4E (0.50) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 | |
| SCHEMBL4853176 | 0.71 | CYP1A2 (0.53) | KDM4EALDH1A1HPGDSMN1; SMN2TDP1 | |
| SCHEMBL2590289 | 0.71 | ALDH1A1 (0.50) | KDM4EALDH1A1GLAHPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0870063-B1 | FLUORESCENCE DETECTION ASSAY FOR HOMOGENEOUS PCR HYBRIDIZATION SYSTEMS | PERKIN ELMER CORP (US) | 2000-07-26 | — | — | EP | claimed |
| EP-0870063-A2 | FLUORESCENCE DETECTION ASSAY FOR HOMOGENEOUS PCR HYBRIDIZATION SYSTEMS | THE PERKIN-ELMER CORPORATION (US) | 1998-10-14 | — | — | EP | claimed |
| US-5716784-A | Fluorescence detection assay for homogeneous PCR hybridization systems | THE PERKIN-ELMER CORPORATION (US) | 1998-02-10 | — | — | US | claimed |
| WO-1997029210-A2 | FLUORESCENCE DETECTION ASSAY FOR HOMOGENEOUS PCR HYBRIDIZATION SYSTEMS | THE PERKIN-ELMER CORPORATION (US) | 1997-08-14 | — | — | WO | claimed |
| US-20080160594-A1 | Methods of Light Activated Release of Ligands from Endosomes | INVITROGEN CORPORATION (US) | 2008-07-03 | — | — | US | disclosed |
| US-20030031655-A1 | Methods of light activated release of ligands from endosomes | SEQUITUR, INC. (US) | 2003-02-13 | — | — | US | disclosed |
| WO-2002062989-A2 | METHODS OF LIGHT ACTIVATED RELEASE 0F LIGANDS FROM ENDOSOMES | SEQUITUR, INC. (US) | 2002-08-15 | — | — | WO | disclosed |
| EP-0870063-B1 | FLUORESCENCE DETECTION ASSAY FOR HOMOGENEOUS PCR HYBRIDIZATION SYSTEMS | PERKIN ELMER CORP (US) | 2000-07-26 | — | — | EP | disclosed |
| EP-0870063-A2 | FLUORESCENCE DETECTION ASSAY FOR HOMOGENEOUS PCR HYBRIDIZATION SYSTEMS | THE PERKIN-ELMER CORPORATION (US) | 1998-10-14 | — | — | EP | disclosed |
| US-5716784-A | Fluorescence detection assay for homogeneous PCR hybridization systems | THE PERKIN-ELMER CORPORATION (US) | 1998-02-10 | — | — | US | disclosed |
| WO-1997029210-A2 | FLUORESCENCE DETECTION ASSAY FOR HOMOGENEOUS PCR HYBRIDIZATION SYSTEMS | THE PERKIN-ELMER CORPORATION (US) | 1997-08-14 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20030031655-A1 | Methods of light activated release of ligands from endosomes | LAMP2, PLAUR, CLTB | KDM4E 4721/4885ALDH1A1 4432/4885GLA 932/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.