SCHEMBL4581010

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4581524	0.93	IL6 (0.73)	IL6FFAR4FFAR1ALDH1A1LMNA
	SCHEMBL4151869	0.91	IL6 (0.75)	IL6FFAR4FFAR1ALDH1A1LMNA
	SCHEMBL4143687	0.89	IL6 (0.74)	IL6FFAR4FFAR1ALDH1A1LMNA
	SCHEMBL4580655	0.89	IL6 (0.77)	IL6FFAR4FFAR1ALDH1A1LMNA
	SCHEMBL4581164	0.89	IL6 (0.69)	IL6ALDH1A1LMNAAKR1C3HPGD
	SCHEMBL4131851	0.89	IL6 (0.73)	IL6FFAR4FFAR1ALDH1A1LMNA
	SCHEMBL4141576	0.88	IL6 (0.81)	IL6FFAR4FFAR1
	SCHEMBL4581073	0.88	IL6 (0.78)	IL6FFAR4FFAR1ALDH1A1
	SCHEMBL4581594	0.87	IL6 (0.73)	IL6ALDH1A1LMNAMAPT
	SCHEMBL4582244	0.87	IL6 (0.70)	IL6ALDH1A1LMNAMAPTNPSR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.