Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP3A4 | P08684 | 2/20 | 0.58 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.47 |
| ▸ | LMNA | P02545 | 5/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | HTT | P42858 | 3/20 | 0.47 |
| ▸ | MAPT | P10636 | 4/20 | 0.46 |
| ▸ | GAA | P10253 | 4/20 | 0.46 |
| ▸ | POLB | P06746 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.46 |
| ▸ | PKM | P14618 | 1/20 | 0.46 |
| ▸ | HPGD | P15428 | 1/20 | 0.46 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.46 |
| ▸ | MPI | P34949 | 1/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.46 |
| ▸ | RAB9A | P51151 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8746896 | 0.89 | CYP3A4 (0.51) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL8746897 | 0.89 | CYP3A4 (0.51) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11454683 | 0.86 | CYP3A4 (0.56) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL6067530 | 0.86 | CYP3A4 (0.56) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| Hydrochloric Acid SCHEMBL11533363 | 0.84 | CYP3A4 (0.55) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL3678614 | 0.81 | CYP3A4 (0.51) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11861746 | 0.81 | CYP3A4 (0.51) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL3678612 | 0.81 | CYP3A4 (0.51) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11864864 | 0.81 | CYP3A4 (0.51) | CYP3A4ADRA2AALDH1A1LMNAKDM4E | |
| SCHEMBL11857218 | 0.81 | CYP3A4 (0.51) | CYP3A4ADRA2AALDH1A1LMNAKDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| JP-57169407-A | — | — | None | — | — | JP | disclosed |
| US-9662309-B2 | Anti-demodicosis agent | BAYER INTELLECTUAL PROPERTY GMBH (DE) | 2017-05-30 | — | — | US | disclosed |
| US-20080039519-A1 | Anti-Demodicosis Agent | BAYER HEALTHCARE AG (DE) | 2008-02-14 | — | — | US | disclosed |
| EP-1811990-A1 | ANTI-DEMODICOSIS AGENT | Bayer HealthCare AG (DE) | 2007-08-01 | — | — | EP | disclosed |
| WO-2006050816-A1 | ANTI-DEMODICOSIS AGENT | BAYER HEALTHCARE AG (DE) | 2006-05-18 | — | — | WO | disclosed |
| JP-S57169407-A | INSECTICIDAL AND MITICIDAL COMPOSITION | NIPPON NOHYAKU CO LTD | 1982-10-19 | — | — | JP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080039519-A1 | Anti-Demodicosis Agent | ACHE, DDT, CYP51A1 | CYP3A4 2514/4885ADRA2A 2003/4885ALDH1A1 1982/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.