Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FNTA | P49354 | 1/20 | 0.46 |
| ▸ | FNTB | P49356 | 1/20 | 0.46 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.42 |
| ▸ | POLB | P06746 | 3/20 | 0.42 |
| ▸ | HTT | P42858 | 1/20 | 0.42 |
| ▸ | RECQL | P46063 | 1/20 | 0.42 |
| ▸ | KMT2A | Q03164 | 5/20 | 0.42 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | MEN1 | O00255 | 4/20 | 0.40 |
| ▸ | PKM | P14618 | 1/20 | 0.40 |
| ▸ | XDH | P47989 | 2/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA1 | P00915 | 1/20 | 0.38 |
| ▸ | CA2 | P00918 | 1/20 | 0.38 |
| ▸ | CA9 | Q16790 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 3/20 | 0.37 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.37 |
| ▸ | GAA | P10253 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4134200 | 0.78 | FNTA (0.48) | FNTAFNTBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL24920108 | 0.78 | NPC1 (0.56) | SMN1; SMN2KDM4EALDH1A1HTTKMT2A | |
| SCHEMBL11899586 | 0.73 | PKM (0.48) | FNTAFNTBKDM4EALDH1A1POLB | |
| SCHEMBL1742738 | 0.73 | PKM (0.48) | FNTAFNTBKDM4EALDH1A1POLB | |
| SCHEMBL2193196 | 0.71 | PKM (0.55) | FNTAFNTBSMN1; SMN2KDM4EALDH1A1 | |
| SCHEMBL30254449 | 0.70 | XDH (0.45) | XDHGAA | |
| SCHEMBL17665507 | 0.69 | MEN1 (0.58) | SMN1; SMN2POLBRECQLKMT2AMEN1 | |
| SCHEMBL8234335 | 0.68 | PKM (0.55) | FNTAFNTBKDM4EALDH1A1POLB | |
| SCHEMBL2075577 | 0.68 | PKM (0.49) | FNTAFNTBKDM4EALDH1A1POLB | |
| SCHEMBL17665629 | 0.68 | LMNA (0.55) | SMN1; SMN2KDM4EALDH1A1POLBKMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1904496-A2 | COMPOSITIONS AND METHODS PERTAINING TO PNA SYNTHONS AND OLIGOMERS COMPRISING A UNIVERSAL BASE | Applera Corporation (US) | 2008-04-02 | — | — | EP | disclosed |
| WO-2006138453-A2 | COMPOSITIONS AND METHODS PERTAINING TO PNA SYNTHONS AND OLIGOMERS COMPRISING A UNIVERSAL BASE | APPLERA CORPORATION (US) | 2006-12-28 | — | — | WO | disclosed |