SCHEMBL4581575

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4131851	0.90	IL6 (0.73)	IL6KCNH2MAPTALDH1A1L3MBTL1
	SCHEMBL4581594	0.90	IL6 (0.73)	IL6KDM4EMAPTALDH1A1KMT2A
	SCHEMBL4582097	0.90	IL6 (0.69)	IL6KCNH2GRIN2B
	SCHEMBL4135439	0.90	IL6 (0.69)	IL6KCNH2GRIN2BSYKKDM4E
	SCHEMBL4135792	0.90	IL6 (0.72)	IL6KDM4EMAPTALDH1A1NPC1
	SCHEMBL4135610	0.89	IL6 (0.68)	IL6SYKKDM4EMAPTALDH1A1
	SCHEMBL4580854	0.89	IL6 (0.71)	IL6KDM4EMAPTPOLBALDH1A1
	SCHEMBL4581352	0.89	IL6 (0.71)	IL6KCNH2GRIN2BKDM4EMAPT
	SCHEMBL4141780	0.88	IL6 (0.69)	IL6
	SCHEMBL4581224	0.88	IL6 (0.72)	IL6GRIN2BKDM4EMAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.