Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ADORA3 | P0DMS8 | 5/20 | 0.49 |
| ▸ | ADORA2A | P29274 | 3/20 | 0.49 |
| ▸ | GMPS | P49915 | 1/20 | 0.49 |
| ▸ | PI4KA | P42356 | 2/20 | 0.47 |
| ▸ | PI4K2B | Q8TCG2 | 2/20 | 0.47 |
| ▸ | PI4K2A | Q9BTU6 | 2/20 | 0.47 |
| ▸ | PI4KB | Q9UBF8 | 2/20 | 0.47 |
| ▸ | SLC28A1 | O00337 | 2/20 | 0.47 |
| ▸ | ADORA1 | P30542 | 2/20 | 0.47 |
| ▸ | DPP4 | P27487 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | MAP3K7 | O43318 | 1/20 | 0.47 |
| ▸ | SLC28A2 | O43868 | 1/20 | 0.47 |
| ▸ | GAPDH | P04406 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | ADORA2B | P29275 | 1/20 | 0.47 |
| ▸ | STAT6 | P42226 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.47 |
| ▸ | DOT1L | Q8TEK3 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7207821 | 0.90 | ADORA3 (0.48) | ADORA3ADORA2AGMPSPI4KAPI4K2B | |
| SCHEMBL2534138 | 0.89 | ADORA3 (0.52) | ADORA3ADORA2AGMPSPI4KAPI4K2B | |
| SCHEMBL29639535 | 0.88 | ADORA3 (0.54) | ADORA3ADORA2AGMPSPI4KAPI4K2B | |
| SCHEMBL2270714 | 0.88 | ADORA3 (0.54) | ADORA3ADORA2AGMPSPI4KAPI4K2B | |
| SCHEMBL6828797 | 0.87 | ADORA3 (0.53) | ADORA3ADORA2AGMPSPI4KAPI4K2B | |
| SCHEMBL3624014 | 0.87 | ADORA2A (0.42) | ADORA3ADORA2AADORA1ADORA2BAHCY | |
| SCHEMBL9512681 | 0.87 | FGFR1 (0.52) | ADORA3ADORA2AGMPSPI4KAPI4K2B | |
| SCHEMBL29509039 | 0.87 | ADORA3 (0.50) | ADORA3ADORA2AGMPSPI4KAPI4K2B | |
| SCHEMBL10786319 | 0.86 | ADORA3 (0.52) | ADORA3ADORA2AGMPSPI4KAPI4K2B | |
| SCHEMBL3698843 | 0.86 | ADORA3 (0.54) | ADORA3ADORA2AGMPSPI4KAPI4K2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114729363-A | IL-34 antisense agents and methods of use thereof | 诺格拉制药有限公司 | 2022-07-08 | — | — | CN | claimed |
| CN-118891366-A | SiRNA inhibiting expression of transferrin receptor 2 | 第一三共株式会社 | 2024-11-01 | — | — | CN | disclosed |
| CN-118871585-A | Chemically-modified oligonucleotides with RNAi activity | 第一三共株式会社 | 2024-10-29 | — | — | CN | disclosed |
| CN-114729363-A | IL-34 antisense agents and methods of use thereof | 诺格拉制药有限公司 | 2022-07-08 | — | — | CN | disclosed |
| CN-114555069-A | Oligonucleotides and methods for treating neurological diseases | 奎里斯公司 | 2022-05-27 | — | — | CN | disclosed |
| US-7371852-B2 | Alkyl-linked nucleotide compositions | SERENEX, INC. (US) | 2008-05-13 | — | — | US | disclosed |
| EP-1585754-A2 | ALKYL-LINKED NUCLEOTIDE COMPOSITIONS | Serenex, Inc. (US) | 2005-10-19 | — | — | EP | disclosed |
| US-20040215009-A1 | Alkyl-linked nucleotide compositions | SERENEX, INC. (US) | 2004-10-28 | — | — | US | disclosed |
| WO-2004065566-A2 | ALKYL-LINKED NUCLEOTIDE COMPOSITIONS | SERENEX, INC. (US) | 2004-08-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040215009-A1 | Alkyl-linked nucleotide compositions | NT5C3B, NUDT1, NT5C2 | ADORA3 124/4885ADORA2A 147/4885GMPS 199/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.