SCHEMBL487136

SCHEMBL487136

CCCCCCCCC(C)(C(=O)OC)C(=O)OC

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MAPT P10636 2/20 0.46
MEN1 O00255 1/20 0.46
KMT2A Q03164 1/20 0.46
ATM Q13315 1/20 0.46
L3MBTL1 Q9Y468 1/20 0.46
GGPS1 O95749 5/20 0.45
EPHX1 P07099 1/20 0.44
CES2 O00748 1/20 0.42
KDM4E B2RXH2 1/20 0.41
TP53 P04637 1/20 0.41
CYP3A4 P08684 1/20 0.41
ALOX15 P16050 1/20 0.41
TSHR P16473 1/20 0.41
ACAT1 P24752 1/20 0.41
SOAT1 P35610 1/20 0.41
USP2 O75604 1/20 0.41
LMNA P02545 1/20 0.41
SMPD1 P17405 1/20 0.40
ZDHHC7 Q9NXF8 1/20 0.40
FDPS P14324 7/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Potassium SCHEMBL29455954 0.96 MAPT (0.44) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL9419471 0.91 CA1 (0.41) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL21054110 0.90 CES2 (0.41) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL18987409 0.88 MEN1 (0.40) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL20822432 0.87 MAPT (0.44) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL18612495 0.85 MAPT (0.47) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL28978239 0.85 MAPT (0.47) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL28723450 0.85 MAPT (0.47) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL14445397 0.85 MAPT (0.47) MAPTMEN1KMT2AATML3MBTL1
SCHEMBL28070477 0.85 MAPT (0.47) MAPTMEN1KMT2AATML3MBTL1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1178031-B1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH MANGANESE CATALYSTS OR THE LIKE DAICEL CHEM (JP) 2012-02-01 EP disclosed
US-6548713-B2 Efficiently producing a compound having an alkyl group or alkenyl group bonded at the alpha position of an electron attractive group, by catalytic radical addition reaction with compound of Group 5,6,7,8, or 9 DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2003-04-15 US disclosed
US-20020165416-A1 Process for the preparation of organic compounds with manganese cataylsts or the like DAICEL CHEMICAL INDUSTRIES, LTD. (JP) 2002-11-07 US disclosed
EP-1178031-A1 PROCESS FOR THE PREPARATION OF ORGANIC COMPOUNDS WITH MANGANESE CATALYSTS OR THE LIKE Daicel Chemical Industries, Ltd. (JP) 2002-02-06 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20020165416-A1 Process for the preparation of organic compounds with manganese cataylsts or the like SOD1, CAT, SOD3 MAPT 2030/4885MEN1 4065/4885KMT2A 1383/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.