Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.43 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | SYK | P43405 | 1/20 | 0.38 |
| ▸ | CA12 | O43570 | 2/20 | 0.38 |
| ▸ | CA1 | P00915 | 2/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
| ▸ | PTPN1 | P18031 | 2/20 | 0.36 |
| ▸ | CDC25B | P30305 | 1/20 | 0.36 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | CA9 | Q16790 | 1/20 | 0.35 |
| ▸ | PTPRC | P08575 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7882885 | 0.89 | ALDH1A1 (0.49) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL7882887 | 0.80 | KMT2A (0.43) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL6741833 | 0.77 | KMT2A (0.48) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL13904629 | 0.77 | ALDH1A1 (0.51) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL27341323 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL27847368 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL27544421 | 0.73 | ALDH1A1 (0.46) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL2847154 | 0.72 | ALDH1A1 (0.59) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL21216606 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A | |
| SCHEMBL3283062 | 0.71 | ALDH1A1 (0.54) | ALDH1A1MAPK1L3MBTL1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7399460-B2 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO INTERNATIONAL B.V. (NL) | 2008-07-15 | — | — | US | disclosed |
| US-20070077197-A1 | Metal Complexes Derivatized with Folate for use in Diagnostic and Therapeutic Applications | BRACCO INTERNATIONAL B.V. (NL) | 2007-04-05 | — | — | US | disclosed |
| US-7186397-B2 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO INTERNATIONAL B.V. (NL) | 2007-03-06 | — | — | US | disclosed |
| US-20010004454-A1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO SUISSE SA (CH) | 2001-06-21 | — | — | US | disclosed |
| US-6221334-B1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | BRACCO RESEARCH USA, INC. | 2001-04-24 | — | — | US | disclosed |
| US-6093382-A | A FOLATE-RECEPTOR BINDING LIGAND COMPRSING ONE OR MORE FOLATE BINDING GROUPS, ATLEAST ONE OF WHICH IS CONJUGATED THROUGH ALPHA CARBOXYLATE VIA A LINKING GROUP TO MACROCYCLIC OR NON MACROCYCLIC METAL CHELATING LIGAND RADICAL | BRACCO RESEARCH USA INC. (US) | 2000-07-25 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070077197-A1 | Metal Complexes Derivatized with Folate for use in Diagnostic and Therapeutic Applications | FOLR1, FOLR2, SLC46A1 | ALDH1A1 782/4885MAPK1 4814/4885L3MBTL1 3717/4885 |
| US-20010004454-A1 | Metal complexes derivatized with folate for use in diagnostic and therapeutic applications | FOLR1, FOLR2, SLC46A1 | ALDH1A1 1176/4885MAPK1 4791/4885L3MBTL1 3025/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.