Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HCRTR1 | O43613 | 1/20 | 0.33 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.33 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.33 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.33 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.32 |
| ▸ | NPY2R | P49146 | 1/20 | 0.32 |
| ▸ | CCR5 | P51681 | 1/20 | 0.32 |
| ▸ | LNPEP | Q9UIQ6 | 2/20 | 0.32 |
| ▸ | GPBAR1 | Q8TDU6 | 1/20 | 0.31 |
| ▸ | ACACB | O00763 | 3/20 | 0.31 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582129 | 1.00 | HCRTR1 (0.33) | HCRTR1HCRTR2CHRM2CHRM3CHRM4 | |
| SCHEMBL2783313 | 0.86 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL2783312 | 0.86 | HCRTR1 (0.31) | HCRTR1HCRTR2 | |
| SCHEMBL2784832 | 0.85 | CCR5 (0.31) | HCRTR1HCRTR2CCR5PTGDR2 | |
| SCHEMBL2784825 | 0.85 | CCR5 (0.31) | HCRTR1HCRTR2CCR5PTGDR2 | |
| SCHEMBL2784829 | 0.85 | CCR5 (0.31) | HCRTR1HCRTR2CCR5PTGDR2 | |
| SCHEMBL2782498 | 0.83 | BMP1 (0.37) | — | |
| SCHEMBL2782495 | 0.83 | BMP1 (0.37) | — | |
| SCHEMBL4581885 | 0.81 | PRMT5 (0.32) | GPBAR1PTGDR2 | |
| SCHEMBL4581873 | 0.81 | PRMT5 (0.32) | GPBAR1PTGDR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1509218-A4 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORP (US) | 2008-03-26 | — | — | EP | disclosed |
| EP-1509218-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SmithKline Beecham Corporation (US) | 2005-03-02 | — | — | EP | disclosed |
| WO-2003101442-A1 | PEPTIDE DEFORMYLASE INHIBITORS | SMITHKLINE BEECHAM CORPORATION (US) | 2003-12-11 | — | — | WO | disclosed |