Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNFRSF1A | P19438 | 1/20 | 0.32 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 4/20 | 0.32 |
| ▸ | HTR2A | P28223 | 4/20 | 0.31 |
| ▸ | PRKDC | P78527 | 1/20 | 0.30 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL680571 | 0.87 | TDP1 (0.37) | TNFRSF1ATDP1PTPN1HTR2APRKDC | |
| SCHEMBL2764142 | 0.87 | TDP1 (0.37) | TNFRSF1ATDP1PTPN1HTR2APRKDC | |
| SCHEMBL7645902 | 0.79 | HTR2A (0.43) | TDP1HTR2ATAAR1 | |
| SCHEMBL2053675 | 0.73 | CYP3A4 (0.43) | TDP1 | |
| SCHEMBL2804053 | 0.72 | TDP1 (0.46) | TDP1 | |
| SCHEMBL1900134 | 0.71 | CYP3A4 (0.42) | TDP1HTR2A | |
| SCHEMBL16432304 | 0.71 | CYP3A4 (0.39) | TDP1 | |
| SCHEMBL2037739 | 0.71 | LMNA (0.46) | TDP1PRKDC | |
| SCHEMBL28083440 | 0.71 | CYP3A4 (0.43) | TDP1 | |
| SCHEMBL7475244 | 0.71 | ALDH1A1 (0.47) | TDP1PRKDC |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20080226941-A1 | Solvent Mixtures For Organic Semiconductors | MERCK PATENT GMBH (DE) | 2008-09-18 | — | — | US | disclosed |