Aniline

Aniline

SCHEMBL4582474

NS(N)(=O)=O.Nc1ccccc1

nearest known ligand 0.69

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 3/20 0.69
CA1 P00915 10/20 0.52
CA2 P00918 10/20 0.52
CA9 Q16790 9/20 0.52
CA12 O43570 6/20 0.52
CA14 Q9ULX7 5/20 0.52
CA5A P35218 5/20 0.52
CA4 P22748 4/20 0.52
CA6 P23280 3/20 0.52
CA7 P43166 3/20 0.52
CA5B Q9Y2D0 3/20 0.52
CA13 Q8N1Q1 2/20 0.52
CA3 P07451 1/20 0.52
PLA2G7 Q13093 1/20 0.52
TDP1 Q9NUW8 2/20 0.50
USP2 O75604 1/20 0.50
AGO2 Q9UKV8 1/20 0.50
CYP3A4 P08684 2/20 0.48
TAAR1 Q96RJ0 1/20 0.48
HSD17B10 Q99714 1/20 0.48

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Aniline SCHEMBL3156113 0.88 TSHR (0.61) TSHRCA1CA2CA9CA12
Aniline SCHEMBL676147 0.85 TSHR (0.65) TSHRCA1CA2CA9CA12
Aniline SCHEMBL167326 0.85 TSHR (0.65) TSHRCA1CA2CA9CA12
Aniline SCHEMBL28692745 0.85 TSHR (0.65) TSHRCA1CA2CA9CA12
Aniline SCHEMBL10500825 0.85 TSHR (0.65) TSHRCA1CA2CA9CA12
Aniline SCHEMBL167327 0.85 TSHR (0.65) TSHRCA1CA2CA9CA12
SCHEMBL18517570 0.83 TSHR (1.00) TSHRTDP1CYP3A4TAAR1HSD17B10
SCHEMBL22096536 0.83 TSHR (1.00) TSHRTDP1CYP3A4TAAR1HSD17B10
Aniline SCHEMBL11803 0.83
Aniline SCHEMBL9755597 0.83 TSHR (1.00) TSHRTDP1CYP3A4TAAR1HSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-5543147-A ANTIINFLAMMATORY AND WOUND HEALING ACITIVITY Leonidov, Nikolai B. (RU) 1996-08-06 US claimed
EP-0638558-A1 CRYSTALLINE MODIFICATION OF 2,4-DIOXO-6-METHYL-1,2,3,4-TETRAHYDROPYRIMIDINE, METHOD OF OBTAINING THE SAME AND A PHARMACEUTICAL PREPARATION BASED ON IT LEONIDOV, Nikolai Borisovich (RU) 1995-02-15 EP claimed
US-4120855-A Bactericidally active monochlorotriazine dyes LIVERANT VLADIMIR LEIBOVICH 1978-10-17 US claimed
CN-103030714-B Preparation method of low-molecular-weight chitosan oligosaccharide sulfamide derivate with hypoglycemic activity UNIV JIANGNAN 2014-09-24 CN disclosed
CN-103030714-A Preparation method of low-molecular-weight chitosan oligosaccharide sulfamide derivate with hypoglycemic activity UNIV JIANGNAN 2013-04-10 CN disclosed
WO-2008123799-A1 MODIFIED ARABINOGALACTANS AND A METHOD FOR THE THE PRODUCTION THEREOF INSTITUT NEFTEKHIMII I KATALIZA ROSSIISKOI AKADEMII NAUK (RU) 2008-10-16 WO disclosed
EP-0724888-B1 WOUND COVERING MATERIAL AND WOUND COVERING COMPOSITION OGITA BIOMATERIAL LAB CO LTD (JP) 2003-05-21 EP disclosed
US-20020028232-A1 Wound dressing KUBOTA SUNAO (JP) 2002-03-07 US disclosed
US-5834007-A Wound-covering material and wound-covering composition OGITA BIOMATERIAL LABORATORIES CO. LTD. (JP) 1998-11-10 US disclosed
EP-0553569-B1 Method for processing silver halide color photographic light-sensitive materials KONISHIROKU PHOTO IND (JP) 1996-12-04 EP disclosed
EP-0724888-A1 WOUND COVERING MATERIAL AND WOUND COVERING COMPOSITION Kubota, Sunao (JP) 1996-08-07 EP disclosed
US-4395527-A POLYIMIDES FROM AMINOPOLYSILOXANES M & T CHEMICALS INC. (US) 1983-07-26 US disclosed
EP-0054426-A2 Improvements in or relating to siloxanes M & T CHEMICALS, INC. (US) 1982-06-23 EP disclosed
US-4331596-A Arylazoarylazo-substituted azo, azomethine 1:2 chromium complex dyes CIBA-GEIGY CORPORATION (US) 1982-05-25 US disclosed
US-4315854-A Chromium and cobalt complex amino hydroxy azomethine dyes CIBA-GEIGY CORPORATION (US) 1982-02-16 US disclosed
EP-0018939-A1 1:2 Metal complex dyestuffs of azomethines, process for their preparation and process for dyeing and printing by using these dyestuffs CIBA-GEIGY AG (CH) 1980-11-12 EP disclosed
EP-0001614-A1 Water-soluble, fibre-reactive, green azo-phthalocyanine dyestuffs, their preparation and their application, as well as the phthalocyanine pyrazolone intermediates and their preparation CASSELLA Aktiengesellschaft (DE) 1979-05-02 EP disclosed
US-4120855-A Bactericidally active monochlorotriazine dyes LIVERANT VLADIMIR LEIBOVICH 1978-10-17 US disclosed
US-4116952-A POLYAMIDES CIBA-GEIGY CORPORATION (US) 1978-09-26 US disclosed
US-4033942-A Chromium complex dye, including azo and azo methine dye compounds CIBA-GEIGY AG (CH) 1977-07-05 US disclosed