Known targets — ChEMBL curated mechanism
ADRA1AADRA1BADRA1DADRA2AADRA2BADRA2CADRB1ADRB2ADRB3CALCRLCHRM1CHRM2CHRM3F2RMAOAMAOBMAP2K1MAP2K2NTRK1NTRK2NTRK3OPRD1OPRK1OPRM1P2RY12PKLRSCN10ASCN11ASCN1ASCN2ASCN3ASCN4ASCN5ASCN7ASCN8ASCN9ASLC18A2SLC6A2SLC6A3TLR7TLR9TUBA1ATUBA1BTUBA1CTUBA3CTUBA3ETUBA4ATUBBTUBB1TUBB2ATUBB2BTUBB3TUBB4ATUBB4BTUBB6TUBB8dacAdacBdacCfolAftsImrcAmrcBmrdApolrplArplBrplCrplDrplErplFrplIrplJrplKrplLrplMrplNrplOrplPrplQrplRrplSrplTrplUrplVrplWrplXrplYrpmArpmBrpmB1rpmB2rpmCrpmDrpmErpmE2rpmFrpmGrpmG1rpmG2rpmHrpmIrpmJrpmJ2rpsArpsBrpsCrpsDrpsErpsFrpsGrpsHrpsIrpsJrpsKrpsLrpsMrpsNrpsOrpsPrpsQrpsRrpsR1rpsR2rpsSrpsTrpsUrpsZykgMykgO
The experimentally established mechanism targets of Aniline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL167327 | 1.00 | TSHR (0.65) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL676147 | 1.00 | TSHR (0.65) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL5693986 | 0.97 | TSHR (0.61) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL28037884 | 0.97 | TSHR (0.61) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL28305697 | 0.95 | TSHR (0.58) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL3156113 | 0.92 | TSHR (0.61) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL7863425 | 0.90 | TSHR (0.52) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL8022436 | 0.90 | TSHR (0.52) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL3783271 | 0.89 | TSHR (0.58) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL6026655 | 0.89 | TSHR (0.58) | TSHRALDH1A1NT5EHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 48 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119584440-A | Processing method of large back cavity circuit board | 东莞市科佳电路有限公司 | 2025-03-07 | — | — | CN | disclosed |
| CN-112074736-B | UV filter composition, method for the production thereof and use thereof | 巴斯夫欧洲公司 | 2024-10-01 | — | — | CN | disclosed |
| US-11793742-B2 | Mixtures of cosmetic UV absorbers | BASF SE (DE) | 2023-10-24 | — | — | US | disclosed |
| US-11666050-B2 | Enhancing the antimicrobial activity of biocides with polymers | BASF SE (DE) | 2023-06-06 | — | — | US | disclosed |
| US-11647746-B2 | Enhancing the antimicrobial activity of biocides with polymers | BASF SE (DE) | 2023-05-16 | — | — | US | disclosed |
| US-11458083-B2 | Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities | L'OREAL (FR) | 2022-10-04 | — | — | US | disclosed |
| US-20220047483-A1 | MICRO-PARTICULATE ORGANIC UV ABSORBER COMPOSITION | BASF SE (DE) | 2022-02-17 | — | — | US | disclosed |
| EP-2315502-B1 | Electroluminescent device | UDC IRELAND LTD (IE) | 2020-10-14 | — | — | EP | disclosed |
| EP-2265092-B1 | Electroluminescent device | UDC IRELAND LTD (IE) | 2018-03-14 | — | — | EP | disclosed |
| EP-1520450-B1 | ELECTROLUMINESCENT DEVICE | UDC IRELAND LTD (IE) | 2017-08-02 | — | — | EP | disclosed |
| CN-1654337-A | Method for preparing iron oxide black by reducing nitrobenzene using ferrous powder with side product of aniline sulfate salts | HUBEI KAIYUAN CHEMICALS & TECH (CN) | 2005-08-17 | — | — | CN | disclosed |
| US-20050175856-A1 | Blue emitting, durable, organoelectrouminescent layers containing 2H-benzotriazole compounds; full color display panels; light emission efficiency and brightness | UDC IRELAND LIMITED (IE) | 2005-08-11 | — | — | US | disclosed |
| EP-1520450-A1 | ELECTROLUMINESCENT DEVICE | Ciba Specialty Chemicals Holding Inc. (CH) | 2005-04-06 | — | — | EP | disclosed |
| WO-2003105538-A1 | ELECTROLUMINESCENT DEVICE | SIBA SPELCIALTY CHEMICALS HOLDING INC. (CH) | 2003-12-18 | — | — | WO | disclosed |
| US-5874547-A | REACTING A PRIMARY AROMATIC AMINE WITH DIAZOTIZING AGENT IN SOLUTION; AZO DYES | CROMPTON & KNOWLES CORPORATION (US) | 1999-02-23 | — | — | US | disclosed |
| US-5344980-A | Process for the preparation of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORP. (US) | 1994-09-06 | — | — | US | disclosed |
| US-5300698-A | Process for the prepartion of 1,3,5-tris(4'-hydroxyaryl)benzene | HOECHST CELANESE CORPORATION (US) | 1994-04-05 | — | — | US | disclosed |
| US-4447368-A | Process for the preparation of aminoarylsulphonic acids in sulfolene solvent | SIEMENS-ALLIS, INC. (US) | 1984-05-08 | — | — | US | disclosed |
| US-4435336-A | FROM ARYLAMINE AND SULFONIC ACID, OR CORRESPONDING ARYLAMMONIUM HY | BAYER AKTIENGESELLSCHAFT (DE) | 1984-03-06 | — | — | US | disclosed |
| EP-0000247-B1 | WATER-ABSORBENT STARCH COPOLYMERISATES AND METHOD FOR THEIR PREPARATION. | A.E. STALEY MANUFACTURING COMPANY (US) | 1982-08-04 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11458083-B2 | Cosmetic and/or dermatological composition containing a merocyanine derivative comprising specific polar groups consisting of hydroxyl- and ether-functionalities | KRT18, LAGE3, TYR | TSHR 3849/4885ALDH1A1 1018/4885NT5E 4261/4885 |
| US-11647746-B2 | Enhancing the antimicrobial activity of biocides with polymers | CAT, AOC1, DDT | TSHR 3558/4885ALDH1A1 787/4885NT5E 950/4885 |
| US-20220047483-A1 | MICRO-PARTICULATE ORGANIC UV ABSORBER COMPOSITION | MCM4, UGT1A4, CCNB1 | TSHR 4166/4885ALDH1A1 454/4885NT5E 4667/4885 |
| US-11666050-B2 | Enhancing the antimicrobial activity of biocides with polymers | CAT, AOC1, DDT | TSHR 3558/4885ALDH1A1 787/4885NT5E 950/4885 |
| US-11793742-B2 | Mixtures of cosmetic UV absorbers | BTD, TMSB10, TH | TSHR 1026/4885ALDH1A1 734/4885NT5E 1931/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.