Known targets — ChEMBL curated mechanism
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
The experimentally established mechanism targets of Aniline. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TSHR | P16473 | 7/20 | 0.65 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.52 |
| ▸ | NT5E | P21589 | 1/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.50 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.46 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 4/20 | 0.45 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.45 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.45 |
| ▸ | GAA | P10253 | 1/20 | 0.45 |
| ▸ | BLM | P54132 | 1/20 | 0.45 |
| ▸ | GFER | P55789 | 1/20 | 0.45 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.45 |
| ▸ | MEN1 | O00255 | 1/20 | 0.44 |
| ▸ | CA12 | O43570 | 2/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Aniline SCHEMBL167326 | 1.00 | TSHR (0.65) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL676147 | 1.00 | TSHR (0.65) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL5693986 | 0.97 | TSHR (0.61) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL28037884 | 0.97 | TSHR (0.61) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL28305697 | 0.95 | TSHR (0.58) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL3156113 | 0.92 | TSHR (0.61) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL7863425 | 0.90 | TSHR (0.52) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL8022436 | 0.90 | TSHR (0.52) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL3783271 | 0.89 | TSHR (0.58) | TSHRALDH1A1NT5EHSD17B10TDP1 | |
| Aniline SCHEMBL6026655 | 0.89 | TSHR (0.58) | TSHRALDH1A1NT5EHSD17B10TDP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 211 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20250251347-A1 | PORTABLE LIQUID ANALYZER | VERITEQUE USA INC (US) | 2025-08-07 | — | — | US | claimed |
| CN-119584440-A | Processing method of large back cavity circuit board | 东莞市科佳电路有限公司 | 2025-03-07 | — | — | CN | claimed |
| CN-119431117-A | Method for refining coking o-cresol | 煤炭科学技术研究院有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-119431120-A | Process for producing o-methylbenzylalkyl ether and 2, 6-dimethylbenzene alkyl ether | 煤炭科学技术研究院有限公司 | 2025-02-14 | — | — | CN | claimed |
| CN-118702096-A | Method for recycling battery negative electrode graphite, regenerated graphite material prepared by method and application of regenerated graphite material | 广东邦普循环科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| CN-118702147-A | Method for removing alkali from garnet type solid electrolyte | 山东创鲁先进电池科技有限公司 | 2024-09-27 | — | — | CN | claimed |
| EP-2997360-B1 | DISPOSABLE AND DISPERSIBLE EXPLOSIVE DETECTION DEVICE AND METHOD OF SIMULTANEOUS DETECTION OF EXPLOSIVES | THE DIRECTOR GENERAL DEFENCE RES & DEVELOPMENT ORGANISATION DRDO (IN) | 2024-07-24 | — | — | EP | claimed |
| US-11940387-B2 | Portable liquid analyzer | VERITEQUE USA, INC. (US) | 2024-03-26 | — | — | US | claimed |
| CN-116874047-A | Preparation method of carbon-coated nickel-nitrogen functionalized carbon-doped titanium nitride integral electrode | 内蒙古大学 | 2023-10-13 | — | — | CN | claimed |
| CN-116730795-A | Synthesis method of trifluoro-phenylacetic acid intermediate 1,2, 4-trifluoro-benzene | 山东国邦药业有限公司 | 2023-09-12 | — | — | CN | claimed |
| WO-2005063719-A1 | SUBSTITUTED DIHYDROPYRIMIDINONE PREPARATION USING POLYANILINE SALT CATALYST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2005-07-14 | — | — | WO | claimed |
| EP-1462448-A1 | Process for preparing substituted coumarins | Council of Scientific and Industrial Research (IN) | 2004-09-29 | — | — | EP | claimed |
| US-6743942-B1 | ENVIRONMENTAL SAFETY; EASY SEPARATION, REGENERATION AND REUSE | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2004-06-01 | — | — | US | claimed |
| US-20040092763-A1 | PROCESS FOR THE TRANSESTERIFICATION OF KETO ESTER WITH ALCOHOL USING POLYANILINE SALTS AS CATALYST | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH | 2004-05-13 | — | — | US | claimed |
| US-6716996-B1 | POLYANILINE SALT CATALYTIC CYCLIZATION OF PHENOL AND KETO ESTER | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2004-04-06 | — | — | US | claimed |
| US-20040049068-A1 | Process for preparation of cinnamates using polyaniline salts as catalysts | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2004-03-11 | — | — | US | claimed |
| WO-2002079138-A1 | A PROCESS FOR PREPARATION OF AN ESTER USING A POLYANALINE SALT AS CATALYST | COUNCIL OF SCIENTIFIC AND INDUSTRIAL RESEARCH (IN) | 2002-10-10 | — | — | WO | claimed |
| US-6350896-B1 | POLYANILINE SALTS WITH HYDROCHLORIC ACID OR CARBOXYLIC ACIDS | COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH (IN) | 2002-02-26 | — | — | US | claimed |
| EP-0063270-B1 | PROCESS FOR PREPARING P-SULFANILIC ACID | BAYER AG (DE) | 1985-01-02 | — | — | EP | claimed |
| EP-0063270-A1 | Process for preparing p-sulfanilic acid | BAYER AG (DE) | 1982-10-27 | — | — | EP | claimed |