Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GNRHR | P30968 | 1/20 | 0.37 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.36 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.36 |
| ▸ | AVPR2 | P30518 | 1/20 | 0.35 |
| ▸ | AVPR1A | P37288 | 1/20 | 0.35 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.35 |
| ▸ | APEX1 | P27695 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.34 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.34 |
| ▸ | NR1I2 | O75469 | 3/20 | 0.34 |
| ▸ | CASR | P41180 | 2/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | ALPL | P05186 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4583334 | 0.87 | NOTUM (0.38) | NOTUMHSP90AA1NPSR1L3MBTL1LMNA | |
| SCHEMBL4582299 | 0.81 | NPSR1 (0.37) | NPSR1L3MBTL1 | |
| SCHEMBL2353154 | 0.80 | APEX1 (0.44) | NOTUMHSP90AA1PTGS1APEX1SMN1; SMN2 | |
| SCHEMBL4582481 | 0.79 | NPSR1 (0.36) | NPSR1L3MBTL1TDP1KMT2A | |
| SCHEMBL4582132 | 0.79 | DRD1 (0.34) | NPSR1L3MBTL1 | |
| SCHEMBL4582968 | 0.78 | USP1 (0.33) | — | |
| SCHEMBL4608946 | 0.77 | TYMP (0.46) | NPSR1L3MBTL1SMN1; SMN2LMNATDP1 | |
| SCHEMBL4582691 | 0.75 | IKBKE (0.45) | NOTUMNPSR1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL4584726 | 0.71 | TYMP (0.45) | NOTUMHSP90AA1L3MBTL1SMN1; SMN2LMNA | |
| SCHEMBL2347368 | 0.70 | CYP11B1 (0.39) | NOTUMAPEX1L3MBTL1SMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |