Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IKBKE | Q14164 | 1/20 | 0.45 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.41 |
| ▸ | NOTUM | Q6P988 | 1/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.39 |
| ▸ | POLB | P06746 | 1/20 | 0.39 |
| ▸ | APOBEC3G | Q9HC16 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 2/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.37 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.37 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.37 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.37 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.37 |
| ▸ | HSD17B1 | P14061 | 4/20 | 0.37 |
| ▸ | HSD17B2 | P37059 | 3/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4582481 | 0.82 | NPSR1 (0.36) | KMT2APOLBNPSR1L3MBTL1 | |
| SCHEMBL4583334 | 0.77 | NOTUM (0.38) | NOTUMKMT2AALDH1A1POLBHTT | |
| SCHEMBL4608946 | 0.77 | TYMP (0.46) | KMT2AALDH1A1POLBHTTMEN1 | |
| SCHEMBL2352827 | 0.75 | IKBKE (0.45) | IKBKEADORA3NOTUMKMT2AALDH1A1 | |
| SCHEMBL4582585 | 0.75 | GNRHR (0.37) | NOTUMKMT2AMEN1NPSR1L3MBTL1 | |
| SCHEMBL4582299 | 0.73 | NPSR1 (0.37) | NPSR1L3MBTL1 | |
| SCHEMBL4582132 | 0.71 | DRD1 (0.34) | PGRNPSR1L3MBTL1 | |
| SCHEMBL4582968 | 0.71 | USP1 (0.33) | — | |
| SCHEMBL17637927 | 0.68 | AKT2 (0.63) | KMT2AALDH1A1POLBHTTMEN1 | |
| SCHEMBL11628214 | 0.67 | NOTUM (0.48) | IKBKEADORA3NOTUMALDH1A1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |