SCHEMBL4582772

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL4582381	0.94	IL6 (0.69)	IL6FFAR1FFAR4BTKALDH1A1
	SCHEMBL4582244	0.90	IL6 (0.70)	IL6ALDH1A1GLAMAPTNPSR1
	SCHEMBL4131851	0.89	IL6 (0.73)	IL6FFAR1FFAR4ALDH1A1MAPT
	SCHEMBL4581594	0.89	IL6 (0.73)	IL6ALDH1A1ESR1MAPTLMNA
	SCHEMBL4581224	0.89	IL6 (0.72)	IL6ALDH1A1ESR1MAPTNPSR1
	SCHEMBL4135792	0.89	IL6 (0.72)	IL6ALDH1A1ESR1MAPTLMNA
	SCHEMBL4148280	0.89	IL6 (0.74)	IL6BTKALDH1A1MAPTLMNA
	SCHEMBL4581073	0.88	IL6 (0.78)	IL6FFAR1FFAR4ALDH1A1GRIN1
	SCHEMBL4141576	0.88	IL6 (0.81)	IL6FFAR1FFAR4GRIN1GRIN2B
	SCHEMBL4580854	0.88	IL6 (0.71)	IL6ALDH1A1ESR1MAPTLMNA

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.