Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | CTSL | P07711 | 4/20 | 0.39 |
| ▸ | CTSS | P25774 | 4/20 | 0.39 |
| ▸ | CTSB | P07858 | 3/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | AKT1 | P31749 | 2/20 | 0.38 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.37 |
| ▸ | ATM | Q13315 | 1/20 | 0.37 |
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CTSK | P43235 | 1/20 | 0.35 |
| ▸ | SSTR4 | P31391 | 1/20 | 0.35 |
| ▸ | PPARA | Q07869 | 2/20 | 0.35 |
| ▸ | PPARG | P37231 | 1/20 | 0.35 |
| ▸ | SYK | P43405 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18342304 | 0.83 | MC4R (0.39) | KMT2AEPHX2SSTR4 | |
| SCHEMBL1720924 | 0.83 | MC4R (0.39) | KMT2AEPHX2SSTR4 | |
| SCHEMBL2012019 | 0.81 | KDM1A (0.39) | CA12CA1CA7CA14KMT2A | |
| SCHEMBL462003 | 0.81 | IDO1 (0.36) | CA12CA1CA7CA14CTSL | |
| SCHEMBL462095 | 0.79 | RORC (0.36) | CA12CA1CA7CA14CTSL | |
| SCHEMBL2013227 | 0.79 | CA12 (0.34) | CA12CA1CA7CA14CTSL | |
| SCHEMBL2226908 | 0.79 | KMT2A (0.36) | CA12CA1CA7CA14KMT2A | |
| SCHEMBL1721451 | 0.79 | AKT1 (0.37) | CA12CA1CA7CA14CTSL | |
| SCHEMBL2480628 | 0.79 | KMT2A (0.40) | CA12CA1CA7CA14CTSL | |
| SCHEMBL2476094 | 0.79 | KMT2A (0.40) | CA12CA1CA7CA14CTSL |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |