Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IDO1 | P14902 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 1/20 | 0.35 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA7 | P43166 | 1/20 | 0.35 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.35 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.35 |
| ▸ | TSHR | P16473 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | AKT1 | P31749 | 2/20 | 0.34 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.34 |
| ▸ | CTSS | P25774 | 3/20 | 0.34 |
| ▸ | CTSL | P07711 | 3/20 | 0.34 |
| ▸ | CTSB | P07858 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.34 |
| ▸ | RORC | P51449 | 1/20 | 0.34 |
| ▸ | ATM | Q13315 | 1/20 | 0.33 |
| ▸ | PKM | P14618 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL462095 | 0.93 | RORC (0.36) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL1726610 | 0.91 | KMT2A (0.37) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL1720734 | 0.91 | KMT2A (0.40) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL459152 | 0.91 | CTSS (0.36) | CA12CA1CA7CA14KMT2A | |
| SCHEMBL459500 | 0.90 | HTT (0.34) | CA12CA1CA7CA14KMT2A | |
| SCHEMBL457233 | 0.89 | KMT2A (0.32) | IDO1CA12CA1CA7CA14 | |
| SCHEMBL2013227 | 0.85 | CA12 (0.34) | CA12CA1CA7CA14KMT2A | |
| SCHEMBL2016334 | 0.83 | SLC6A2 (0.39) | KMT2AL3MBTL1 | |
| SCHEMBL2012019 | 0.82 | KDM1A (0.39) | CA12CA1CA7CA14KMT2A | |
| SCHEMBL458294 | 0.81 | CA12 (0.39) | IDO1CA12CA1CA7CA14 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2011147951-A1 | CYCLOAMINO DERIVATIVES AS GPR119 ANTAGONISTS | PROSIDION LIMITED (GB) | 2011-12-01 | — | — | WO | disclosed |