Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 3/20 | 0.52 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.52 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.47 |
| ▸ | PLOD2 | O00469 | 1/20 | 0.47 |
| ▸ | PLOD3 | O60568 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | HPGD | P15428 | 1/20 | 0.47 |
| ▸ | PLOD1 | Q02809 | 1/20 | 0.47 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.47 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.47 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.47 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | CES2 | O00748 | 1/20 | 0.46 |
| ▸ | CES1 | P23141 | 1/20 | 0.46 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.45 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL458300 | 0.86 | TDP1 (0.61) | MEN1KMT2AALDH1A1CYP3A4CYP2D6 | |
| SCHEMBL11820789 | 0.81 | ALDH1A1 (0.55) | KMT2AALDH1A1CYP3A4CYP1A2CYP2C9 | |
| Hydrochloric Acid SCHEMBL11168692 | 0.80 | ALDH1A1 (0.53) | KMT2AALDH1A1CYP3A4CYP1A2CYP2C9 | |
| SCHEMBL10946544 | 0.79 | GAA (0.54) | MEN1KMT2AALDH1A1L3MBTL1TDP1 | |
| SCHEMBL11750676 | 0.79 | CES2 (0.50) | MEN1KMT2AALDH1A1CYP3A4HPGD | |
| SCHEMBL2524805 | 0.79 | LMNA (0.74) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8924416 | 0.79 | L3MBTL1 (0.77) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL8101551 | 0.78 | MEN1 (0.52) | MEN1KMT2AALDH1A1CYP3A4CYP1A2 | |
| SCHEMBL11750814 | 0.78 | KMT2A (0.50) | MEN1KMT2AALDH1A1HPGDL3MBTL1 | |
| SCHEMBL11753603 | 0.78 | TDP1 (0.47) | MEN1KMT2AALDH1A1CYP3A4HPGD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | PHARMACIA CORPORATION | 2007-04-05 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070078146-A1 | Antiinflamamtory agents; antiarthritic agents; inflammatory bowel disorders; multiple sclerosis; asthma | MAPK1, MAPK3, MAPK4 | MEN1 3032/4885KMT2A 1449/4885ALDH1A1 1079/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.