SCHEMBL45831

SCHEMBL45831

CC(C)(C1CCC(c2ccc(O)cc2)(c2ccc(O)cc2)CC1)C1CCC(c2ccc(O)cc2)(c2ccc(O)cc2)CC1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR2 Q92731 13/20 0.53
ESR1 P03372 7/20 0.53
LMNA P02545 1/20 0.34
TYR P14679 1/20 0.34
CYP3A4 P08684 1/20 0.34
AR P10275 1/20 0.34
HPGD P15428 1/20 0.34
TSHR P16473 1/20 0.34
SLC6A2 P23975 1/20 0.34
SLC6A4 P31645 1/20 0.34
HTR6 P50406 1/20 0.34
ESRRG P62508 1/20 0.34
SLC6A3 Q01959 1/20 0.34
HSD17B10 Q99714 1/20 0.34
OPRM1 P35372 2/20 0.34
OPRD1 P41143 1/20 0.34
OPRK1 P41145 1/20 0.34
GRIN2D O15399 1/20 0.33
GRIN3B O60391 1/20 0.33
CHRM2 P08172 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2605552 0.98 ESR2 (0.52) ESR2ESR1LMNATYRCYP3A4
SCHEMBL25767034 0.93 ESR2 (0.47) ESR2ESR1OPRM1
SCHEMBL9065276 0.93 ESR2 (0.55) ESR2ESR1LMNAOPRM1OPRD1
SCHEMBL20684752 0.93 ESR2 (0.47) ESR2ESR1CYP3A4OPRM1OPRD1
SCHEMBL25767236 0.92 ESR2 (0.46) ESR2ESR1OPRM1OPRD1OPRK1
SCHEMBL2605553 0.91 ESR2 (0.49) ESR2ESR1CYP3A4OPRM1OPRD1
SCHEMBL23250802 0.89 ESR2 (0.46) ESR2ESR1LMNATYRCYP3A4
SCHEMBL2498416 0.89 ESR2 (0.53) ESR2ESR1LMNATYRCYP3A4
SCHEMBL24299168 0.88 ESR2 (0.42) ESR2ESR1TSHRHSD17B10
SCHEMBL11141715 0.87 ESR2 (0.44) ESR2ESR1LMNATYRCYP3A4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 3464 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104812796-B Polycarbonate resin, polycarbonate resin composition, and molded article 出光兴产株式会社 2019-07-12 CN claimed
CN-103391958-B Polycarbonate copolymer, coating liquid using same, electrophotographic photoreceptor, and method for producing polycarbonate copolymer 出光兴产株式会社 2016-08-10 CN claimed
EP-2655383-A2 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX Polymers, Inc. (US) 2013-10-30 EP claimed
US-8530044-B2 Hyperbranched oligomeric phosphonates and compositions including the same FRX POLYMERS, INC. (US) 2013-09-10 US claimed
US-20120171460-A1 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-07-05 US claimed
WO-2012088435-A2 HYPERBRANCHED OLIGOMERIC PHOSPHONATES AND COMPOSITIONS INCLUDING THE SAME FRX POLYMERS, INC. (US) 2012-06-28 WO claimed
EP-1591803-B1 High molecular weight lenses formed from viscosity-specific polycarbonate ESSILOR INT (FR) 2009-07-08 EP claimed
US-7208564-B2 Branched polyformals and copolyformals their preparation and use BAYER MATERIALSCIENCE AG (DE) 2007-04-24 US claimed
US-7135545-B2 Providing a high molecular weight polycarbonate; forming a highly transmissive optical lens by lens shaping ESSILOR INTERNATIONAL COMPAGNIE GENERAL D'OPTIQUE (FR) 2006-11-14 US claimed
US-20050245720-A1 High molecular weight lenses formed from viscosity-specific polycarbonate ESSILOR INTERNATIONAL COMPAGNIE GENERAL D'OPTIQUE (FR) 2005-11-03 US claimed
US-6734278-B2 MELT ESTER INTERCHANGE BAYER AKTIENGESELLSCHAFT (DE) 2004-05-11 US claimed
US-20030139564-A1 Production of polyester carbonates BAYER AKTIENGESELLSCHAFT (DE) 2003-07-24 US claimed
US-5470937-A Liquid crystals IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1995-11-28 US claimed
US-5283314-A Polymerizing an oligomer of a dihydric phenol and a branching agent with a dihydric alcohol and a monohydric phenol with stirring IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1994-02-01 US claimed
US-5112936-A Impact resistant polycarbonates for blow molding IDEMITSU PETROCHEMICAL CO., LTD. (JP) 1992-05-12 US claimed
EP-0021260-B2 Process for the preparation of thermoplastic, branched, aromatic polyphosphonates BAYER AG (DE) 1989-04-19 EP claimed
US-4582893-A Aromatic polyesters which contain terminal or lateral radicals with two conjugated double bonds BAYER AKTIENGESELLSCHAFT (DE) 1986-04-15 US claimed
US-4415719-A HEAT-RESISTANT FIREPROOFING MOLDING MATERIALS; USING A BASIC CATALYST, A DIARYL PHOSPHONATE AND AROMATIC POLYHYDROXY COMPOUND BAYER AKTIENGESELLSCHAFT (DE) 1983-11-15 US claimed
EP-0021260-B1 Process for the preparation of thermoplastic, branched, aromatic polyphosphonates BAYER AG (DE) 1983-04-13 EP claimed
EP-0021260-A1 Process for the preparation of thermoplastic, branched, aromatic polyphosphonates BAYER AG (DE) 1981-01-07 EP claimed