Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 10/20 | 0.44 |
| ▸ | ESR1 | P03372 | 8/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | TYR | P14679 | 1/20 | 0.37 |
| ▸ | GRIN2B | Q13224 | 5/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.36 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.36 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.36 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.36 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.36 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.36 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.36 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.35 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL20684752 | 0.90 | ESR2 (0.47) | ESR2ESR1CYP3A4ALDH1A1GRIN2B | |
| SCHEMBL45831 | 0.87 | ESR2 (0.53) | ESR2ESR1CYP3A4LMNATYR | |
| SCHEMBL2605552 | 0.85 | ESR2 (0.52) | ESR2ESR1CYP3A4LMNATYR | |
| SCHEMBL9065614 | 0.84 | ESR2 (0.44) | ESR2ESR1CYP3A4ALDH1A1LMNA | |
| SCHEMBL11571240 | 0.84 | ESR2 (0.37) | ESR2ESR1CYP3A4ALDH1A1LMNA | |
| SCHEMBL21335140 | 0.82 | LTA4H (0.49) | ESR2ESR1ALDH1A1LMNAGRIN2B | |
| SCHEMBL9065276 | 0.81 | ESR2 (0.55) | ESR2ESR1ALDH1A1LMNAOPRM1 | |
| SCHEMBL13379634 | 0.81 | ESR2 (0.47) | ESR2ESR1CYP3A4ALDH1A1LMNA | |
| SCHEMBL2605554 | 0.79 | ESR2 (0.48) | ESR2ESR1CYP3A4ALDH1A1LMNA | |
| SCHEMBL2605553 | 0.78 | ESR2 (0.49) | ESR2ESR1CYP3A4OPRM1OPRD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0077488-A1 | A process for the preparation of thermoplastic polyphosphonatophenyl ester carbonates | MOBAY CORPORATION (US) | 1983-04-27 | — | — | EP | disclosed |
| US-4381390-A | Thermoplastic polyphosphonatophenyl ester carbonate from aryloxycarbonyloxy-benzoic acid aryl ester and preparation thereof | MOBAY CHEMICAL CORPORATION (US) | 1983-04-26 | — | — | US | disclosed |
| US-4342681-A | Use of organic silicon compounds in combination with oxetane compounds, dioxanes or tetrahydrofuranes for stabilizing and brightening polycarbonates which are free from phosphites and free from boric acid esters | BAYER AKTIENGESELLSCHAFT (DE) | 1982-08-03 | — | — | US | disclosed |