Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ESR2 | Q92731 | 6/20 | 0.47 |
| ▸ | ESR1 | P03372 | 5/20 | 0.47 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.44 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.44 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.44 |
| ▸ | CHRM2 | P08172 | 1/20 | 0.44 |
| ▸ | CHRM1 | P11229 | 1/20 | 0.44 |
| ▸ | GRIN1 | Q05586 | 1/20 | 0.44 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.44 |
| ▸ | GRIN2A | Q12879 | 1/20 | 0.44 |
| ▸ | GRIN2B | Q13224 | 1/20 | 0.44 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.44 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.44 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL45831 | 0.93 | ESR2 (0.53) | ESR2ESR1OPRM1GRIN2DGRIN3B | |
| SCHEMBL2605552 | 0.92 | ESR2 (0.52) | ESR2ESR1OPRM1GRIN2DGRIN3B | |
| SCHEMBL11141715 | 0.90 | ESR2 (0.44) | ESR2ESR1OPRM1GRIN2DGRIN3B | |
| SCHEMBL21335140 | 0.89 | LTA4H (0.49) | ESR2ESR1OPRM1GRIN2DGRIN3B | |
| SCHEMBL9065276 | 0.87 | ESR2 (0.55) | ESR2ESR1OPRM1MAPTALDH1A1 | |
| SCHEMBL2605553 | 0.84 | ESR2 (0.49) | ESR2ESR1OPRM1CYP3A4CYP2C9 | |
| SCHEMBL9065614 | 0.84 | ESR2 (0.44) | ESR2ESR1OPRM1GRIN2DGRIN3B | |
| SCHEMBL12893332 | 0.84 | ESR2 (0.47) | ESR2ESR1OPRM1GRIN2DGRIN3B | |
| SCHEMBL1256648 | 0.84 | ESR2 (0.47) | ESR2ESR1OPRM1GRIN2DGRIN3B | |
| SCHEMBL23250802 | 0.83 | ESR2 (0.46) | ESR2ESR1OPRM1GRIN2BALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3190107-B1 | ARYL COMPOUND SUBSTITUTED WITH GLYCIDYL AND ALLYL GROUPS AS MACROMONOMER FOR HEAT RESISTANT RESIN MATERIALS | SHINETSU CHEMICAL CO (JP) | 2019-01-30 | — | — | EP | disclosed |