Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 1/20 | 0.44 |
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.43 |
| ▸ | MAPT | P10636 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.43 |
| ▸ | ABL1 | P00519 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.42 |
| ▸ | BCR | P11274 | 1/20 | 0.42 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.42 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.42 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.42 |
| ▸ | HPGD | P15428 | 2/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.42 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | RAF1 | P04049 | 1/20 | 0.42 |
| ▸ | GFER | P55789 | 1/20 | 0.42 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.42 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31006744 | 0.84 | APP (0.49) | APPHTR7ALDH1A1MAPTABL1 | |
| SCHEMBL28233631 | 0.83 | HTR7 (0.52) | APPHTR7ALDH1A1ABL1ABCB1 | |
| SCHEMBL13982736 | 0.82 | NPC1 (0.50) | APPTLR8MAPT | |
| SCHEMBL28185641 | 0.82 | APP (0.47) | APPHTR7ALDH1A1MAPTABL1 | |
| SCHEMBL4583260 | 0.80 | ALDH1A1 (0.53) | TLR8ALDH1A1MAPTHPGDPKM | |
| SCHEMBL13982792 | 0.80 | MAPT (0.45) | ALDH1A1MAPTKDM4EHPGDMAPK1 | |
| SCHEMBL13982734 | 0.80 | GRIN2D (0.42) | TLR8ALDH1A1MAPTABL1ABCB1 | |
| SCHEMBL4932114 | 0.77 | KMT2A (0.43) | APPHTR7ALDH1A1MAPTKDM4E | |
| SCHEMBL2495875 | 0.76 | HSD17B10 (0.46) | TLR8ALDH1A1MAPTKDM4EPKM | |
| SCHEMBL16174819 | 0.75 | GAA (0.53) | ALDH1A1MAPTKDM4EPKMMAPK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20180053904-A1 | TETRADENTATE PLATINUM (II) AND PALLADIUM (II) COMPLEXES AND OCTAHEDRAL IRIDIUM COMPLEXES EMPLOYING AZEPINE FUNCTIONAL GROUPS AND THEIR ANALOGUES | ARIZONA BOARD OF REGENTS ON BEHALF OF ARIZONA STATE UNIVERSITY | 2018-02-22 | — | — | US | disclosed |
| WO-2008156656-A2 | METHOD FOR MAKING BIARYL COMPOUNDS, COMPOUNDS MADE BY THE METHOD, AND METHOD FOR THEIR USE | STATE OF OREGON ACTING BY AND THROUGH THE STATE BOARD OF HIGHER EDUCATION ON BEHALF OF OREGON STATE UNIVERSITY (US) | 2008-12-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20180053904-A1 | TETRADENTATE PLATINUM (II) AND PALLADIUM (II) COMPLEXES AND OCTAHEDRAL IRIDIUM COMPLEXES EMPLOYING AZEPINE FUNCTIONAL GROUPS AND THEIR ANALOGUES | AZI2, TPO, LAGE3 | APP 2782/4885HTR7 2141/4885TLR8 4752/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.