SCHEMBL4583693

SCHEMBL4583693

CC1(O)OC(=O)C(c2c(F)cccc2F)=C1c1ccncc1

nearest known ligand 0.47

Predicted protein targets (top 9)

geneUniProtsupporting neighboursconfidence
PTGS2 P35354 18/20 0.47
PTGS1 P23219 5/20 0.45
NPC1 O15118 1/20 0.40
LMNA P02545 1/20 0.40
RAB9A P51151 1/20 0.40
CA1 P00915 1/20 0.38
CA2 P00918 1/20 0.38
CA7 P43166 1/20 0.38
CA9 Q16790 1/20 0.38

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10015964 0.87 PTGS2 (0.56) PTGS2PTGS1CA1CA2CA7
SCHEMBL2350613 0.84 PTGS2 (0.60) PTGS2PTGS1NPC1RAB9A
SCHEMBL4583216 0.77 PTGS2 (0.52) PTGS2PTGS1CA1CA2CA7
SCHEMBL19446292 0.77 PTGS2 (0.55) PTGS2PTGS1NPC1RAB9A
SCHEMBL2354428 0.77 PTGS2 (0.61) PTGS2PTGS1
SCHEMBL3974343 0.75 PTGS2 (0.58) PTGS2PTGS1
SCHEMBL2351999 0.75 PTGS2 (0.56) PTGS2PTGS1
SCHEMBL2351484 0.74 PTGS2 (0.53) PTGS2PTGS1
SCHEMBL4582636 0.74 PTGS2 (0.37) PTGS2PTGS1CA1CA2CA7
SCHEMBL2348407 0.74 PTGS2 (0.57) PTGS2PTGS1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1972623-A1 Arylpyridazines as fungicides Bayer CropScience AG (DE) 2008-09-24 EP disclosed