SCHEMBL4583907

SCHEMBL4583907

CCCCOP(=O)(CCC(N)=O)OCCCC

nearest known ligand 0.47

Predicted protein targets (top 13)

geneUniProtsupporting neighboursconfidence
CYP3A4 P08684 3/20 0.47
LPAR3 Q9UBY5 3/20 0.41
LPAR1 Q92633 2/20 0.41
LPAR2 Q9HBW0 2/20 0.41
MEN1 O00255 1/20 0.39
FAAH O00519 1/20 0.39
TP53 P04637 1/20 0.39
CYP1A2 P05177 1/20 0.39
CYP2C19 P33261 1/20 0.39
SOAT1 P35610 1/20 0.39
KMT2A Q03164 1/20 0.39
TSHR P16473 1/20 0.37
CNR1 P21554 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9819300 0.89 PPARD (0.38) CYP3A4LPAR3LPAR1LPAR2MEN1
SCHEMBL4267682 0.83 CYP3A4 (0.48) CYP3A4MEN1KMT2ATSHR
SCHEMBL5839773 0.80 PPARD (0.56) CYP3A4MEN1FAAHTP53CYP1A2
SCHEMBL11494792 0.80 CYP3A4 (0.45) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL2239484 0.80 DGKA (0.48) CYP3A4LPAR3LPAR1
SCHEMBL10832782 0.80 CYP3A4 (0.64) CYP3A4LPAR3LPAR1LPAR2TSHR
SCHEMBL2350307 0.79 CYP3A4 (0.44) CYP3A4LPAR3LPAR1LPAR2CYP1A2
SCHEMBL15951687 0.79 DGKA (0.47) CYP3A4LPAR3LPAR1LPAR2
SCHEMBL27975578 0.78 AKR1B1 (0.48) CYP3A4MEN1KMT2ATSHR
SCHEMBL11514808 0.78 CYP3A4 (0.61) CYP3A4LPAR3LPAR1LPAR2TSHR

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7396588-B2 Curable composition, varnish and laminate ZEON CORPORATION (JP) 2008-07-08 US disclosed
US-7317046-B2 Cyclic phosphazenes, process for preparing them, flame retardant containing them as active ingredient, and resin composition containing them and molded article therefrom CHEMIPRO KASEI KAISHA, LIMITED (JP) 2008-01-08 US disclosed
US-20070060674-A1 Curable composition, varnish and laminate ZEON CORPRATION (JP) 2007-03-15 US disclosed
US-7160609-B2 Curable composition, varnish, and layered product ZEON CORPORATION (JP) 2007-01-09 US disclosed
US-20050159509-A1 Varnish, shaped item, electrical insulating film, laminate, flame retardant slurry and process for producing flame retardant particles and varnish ZEON CORPORATION (JP) 2005-07-21 US disclosed
US-20040152910-A1 Cyclic phosphazenes, process for preparing them, flame retardants containing the same as the active ingredient, and resin composition containing and molded articles containing the flame retardants CHEMIPRO KASEI KAISHA, LIMITED (JP) 2004-08-05 US disclosed
EP-1403273-A1 CYCLIC PHOSPHAZENES, PROCESS FOR PREPARING THEM, FLAME RETARDANTS CONTAINING THE SAME AS THE ACTIVE INGREDIENT, AND RESIN COMPOSITIONS AND MOLDED ARTICLES CONTAINING THE FLAME RETARDANTS Chemipro Kasei Kaisha, Limited (JP) 2004-03-31 EP disclosed
US-20040025743-A1 Curable composition, varnish, and layered product ZEON CORPORATION (JP) 2004-02-12 US disclosed
US-6139998-A OPTICAL ELEMENTS WITH POLYMER RESIN ON SUBSTRATES INNER SURFACE OF THE CYLINDRICAL SUBSTRATE IS NOT MORE THAN 0.5 .MU.M. THE ELECTROPHOTOGRAPHIC PHOTORECEPTOR EMPLOYING THE SUBSTRATE IS KONICA CORPORATION (JP) 2000-10-31 US disclosed
US-4585703-A MELAMINE RESIN AND PHOSPHONATE FIREPROOFING AGENT DAINIPPON INK & CHEMICALS, INC. (JP) 1986-04-29 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040152910-A1 Cyclic phosphazenes, process for preparing them, flame retardants containing the same as the active ingredient, and resin composition containing and molded articles containing the flame retardants PFAS, AFF1, PHOSPHO1 CYP3A4 2438/4885LPAR3 1741/4885LPAR1 1177/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.