Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GPR35 | Q9HC97 | 14/20 | 0.60 |
| ▸ | POLB | P06746 | 1/20 | 0.44 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.44 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.44 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.42 |
| ▸ | PKM | P14618 | 1/20 | 0.42 |
| ▸ | GSK3B | P49841 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12261076 | 0.82 | GPR35 (0.46) | GPR35POLBTDP1L3MBTL1GSK3B | |
| SCHEMBL1629386 | 0.80 | GPR35 (0.44) | GPR35GSK3B | |
| SCHEMBL3045573 | 0.80 | GPR35 (0.44) | GPR35POLBTDP1L3MBTL1GSK3B | |
| SCHEMBL3836429 | 0.79 | POLB (0.55) | GPR35POLBTDP1L3MBTL1KDM4E | |
| Hydrochloric Acid SCHEMBL7810688 | 0.77 | POLB (0.53) | GPR35POLBTDP1L3MBTL1KDM4E | |
| SCHEMBL2808786 | 0.77 | GSK3B (0.50) | GPR35POLBTDP1L3MBTL1KDM4E | |
| SCHEMBL27363412 | 0.77 | GPR35 (0.46) | GPR35POLBTDP1L3MBTL1KDM4E | |
| SCHEMBL1529989 | 0.77 | MAPT (0.46) | GPR35POLBTDP1KDM4EPKM | |
| SCHEMBL12261073 | 0.77 | GPR35 (0.42) | GPR35POLBGSK3B | |
| SCHEMBL4584130 | 0.76 | GSK3B (0.59) | GPR35POLBTDP1L3MBTL1GSK3B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 110 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2025106014-A1 | COMPOUNDS AND METHODS FOR PKMYT1 INHIBITION | ENGINE BIOSCIENCES PTE. LTD. (SG) | 2025-05-22 | — | — | WO | disclosed |
| US-20240383856-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2024-11-21 | — | — | US | disclosed |
| EP-4192814-B1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2024-08-07 | — | — | EP | disclosed |
| CN-112601751-B | Fused thiophene compounds | 拜欧斯瑞克斯公司 | 2024-04-02 | — | — | CN | disclosed |
| CN-117616011-A | Inhibitors of transglutaminase | 策迪拉有限公司 | 2024-02-27 | — | — | CN | disclosed |
| EP-2970342-B1 | SUBSTITUTED SILAXANTHENIUM RED TO NEAR-INFRARED FLUOROCHROMES FOR IN VITRO AND IN VIVO IMAGING AND DETECTION | VISEN MEDICAL INC (US) | 2024-01-24 | — | — | EP | disclosed |
| WO-2023110138-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-06-22 | — | — | WO | disclosed |
| EP-4192814-A1 | INHIBITORS OF TRANSGLUTAMINASES | Zedira GmbH (DE) | 2023-06-14 | — | — | EP | disclosed |
| WO-2023275337-A1 | INHIBITORS OF TRANSGLUTAMINASES | ZEDIRA GMBH (DE) | 2023-01-05 | — | — | WO | disclosed |
| WO-2022192162-A1 | NOVEL HETEROAROMATIC COMPOUNDS EXHIBITING ANTIFUNGAL ACTIVITY AND THEIR METHOD OF USE | FOX CHASE CHEMICAL DIVERSITY CENTER, INC. (US) | 2022-09-15 | — | — | WO | disclosed |
| CN-1124274-C | 3- (substituted phenyl) -5-thienyl-1, 2, 4-triazole compounds for controlling whitefly | DOW AGROSCIENCES LLC (US) | 2003-10-15 | — | — | CN | disclosed |
| EP-1123290-B1 | 3-(SUBSTITUTED PHENYL)-5-THIENYL-1,2,4-TRIAZOLE COMPOUNDS WITH ACTIVITY AGAINST WHITEFLY | DOW AGROSCIENCES LLC (US) | 2003-02-19 | — | — | EP | disclosed |
| US-6329528-B1 | REACTING ALKYL BENZTHIOIMIDATE OR ITS ACID ADDITION SALT WITH FURAN OR THIOFURAN ACID CHLORIDE COMPOUND TO PRODUCT ADDUCT-INTERMEDIATE; REACTING WITH METHYLHYDRAZINE TO PRODUCE 3-(SUBSTITUTED PHENYL)-5-THIENYL OR FURYL)-1,2,4-TRIAZOLES | DOW AGROSCIENCES LLC | 2001-12-11 | — | — | US | disclosed |
| CN-1324356-A | Process for preparing 3- (substituted phenyl) -5- (thienyl or furyl) -1, 2, 4-triazoles and novel intermediates used therein | DOW AGROSCIENCES CORP (US) | 2001-11-28 | — | — | CN | disclosed |
| CN-1324357-A | 3- (substituted phenyl) -5-thienyl-1, 2, 4-triazole compounds for controlling whitefly | DOW AGROSCIENCES LLC (US) | 2001-11-28 | — | — | CN | disclosed |
| EP-1123291-A1 | PROCESS FOR PREPARING 3-(SUBSTITUTED PHENYL)-5-THIENYL OR FURYL)-1,2,4-TRIAZOLES AND NOVEL INTERMEDIATES UTILIZED THEREIN | Dow Agrosciences LLC (US) | 2001-08-16 | — | — | EP | disclosed |
| EP-1123290-A1 | 3-(SUBSTITUTED PHENYL)-5-THIENYL-1,2,4-TRIAZOLE COMPOUNDS WITH ACTIVITY AGAINST WHITEFLY | Dow AgroSciences LLC (US) | 2001-08-16 | — | — | EP | disclosed |
| US-6265424-B1 | INSECTICIDES, MITICIDES | DOW AGROSCIENCES LLC | 2001-07-24 | — | — | US | disclosed |
| WO-2000024738-A1 | PROCESS FOR PREPARING 3-(SUBSTITUTED PHENYL)-5-THIENYL OR FURYL)-1,2,4-TRIAZOLES AND NOVEL INTERMEDIATES UTILIZED THEREIN | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |
| WO-2000024737-A1 | 3-(SUBSTITUTED PHENYL)-5-THIENYL-1,2,4-TRIAZOLE COMPOUNDS WITH ACTIVITY AGAINST WHITEFLY | DOW AGROSCIENCES LLC (US) | 2000-05-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20240383856-A1 | INHIBITORS OF TRANSGLUTAMINASES | TGM2, TGM3, TGM1 | GPR35 2376/4885POLB 2644/4885TDP1 721/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.