Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MEN1 | O00255 | 1/20 | 0.30 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.30 |
| ▸ | MAPT | P10636 | 1/20 | 0.30 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9913086 | 0.69 | — | — | |
| SCHEMBL20400843 | 0.67 | — | — | |
| SCHEMBL14679918 | 0.61 | — | — | |
| SCHEMBL16724660 | 0.61 | TDP1 (0.34) | ALDH1A1MAPT | |
| SCHEMBL12390891 | 0.61 | MEN1 (0.33) | MEN1ALDH1A1KMT2A | |
| SCHEMBL14392214 | 0.60 | LMNA (0.33) | ALDH1A1MAPT | |
| SCHEMBL12208008 | 0.60 | ACHE (0.44) | MEN1ALDH1A1MAPTKMT2A | |
| SCHEMBL5980626 | 0.59 | TSHR (0.33) | ALDH1A1 | |
| SCHEMBL12208007 | 0.58 | — | — | |
| SCHEMBL7606939 | 0.58 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1968594-A2 | TREATMENT OF OCULAR NEOVASCULAR DISORDERS SUCH AS MACULAR DEGENERATION, ANGIOD STREAKS, UVEITIS AND MACULAR EDEMA | SmithKline Beecham Corporation (US) | 2008-09-17 | — | — | EP | disclosed |
| EP-1954281-A2 | CANCER TREATMENT METHOD | SmithKline Beecham Corporation (US) | 2008-08-13 | — | — | EP | disclosed |
| WO-2007064753-A2 | CANCER TREATMENT METHOD | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2007064752-A2 | TREATMENT OF OCULAR NEOVASCULAR DISORDERS SUCH AS MACULAR DEGENERATION, ANGIOD STREAKS, UVEITIS AND MACULAR EDEMA | SMITHKLINE BEECHAM CORPORATION (US) | 2007-06-07 | — | — | WO | disclosed |
| WO-2006020564-A1 | PYRIMIDIN DERIVATIVES FOR THE TREATMENT OF MULTIPLE MYELOMA | SMITHKLINE BEECHAM CORPORATION (US) | 2006-02-23 | — | — | WO | disclosed |
| EP-1343782-A1 | PYRIMIDINEAMINES AS ANGIOGENESIS MODULATORS | GLAXO GROUP LIMITED (GB) | 2003-09-17 | — | — | EP | disclosed |
| WO-2002059110-A1 | PYRIMIDINEAMINES AS ANGIOGENESIS MODULATORS | GLAXO GROUP LIMITED (GB) | 2002-08-01 | — | — | WO | disclosed |