Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 3/20 | 0.38 |
| ▸ | HPGD | P15428 | 7/20 | 0.37 |
| ▸ | NPC1 | O15118 | 4/20 | 0.37 |
| ▸ | RAB9A | P51151 | 4/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.37 |
| ▸ | TP53 | P04637 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 8/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.36 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.35 |
| ▸ | CYP2A6 | P11509 | 1/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | USP2 | O75604 | 1/20 | 0.32 |
| ▸ | HTT | P42858 | 1/20 | 0.32 |
| ▸ | PKM | P14618 | 1/20 | 0.32 |
| ▸ | CASP3 | P42574 | 1/20 | 0.32 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4610692 | 0.77 | ALDH1A1 (0.37) | HPGDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL4583334 | 0.77 | NOTUM (0.38) | ALDH1A1KDM4EHSD17B10LMNAL3MBTL1 | |
| SCHEMBL19021453 | 0.76 | CNR1 (0.33) | HSD11B1ALDH1A1KDM4ELMNAMAPT | |
| SCHEMBL16996751 | 0.73 | GABRP (0.33) | RAB9AALDH1A1HSD17B10MAPTPOLB | |
| SCHEMBL3614591 | 0.73 | GABRP (0.33) | RAB9AALDH1A1HSD17B10MAPTPOLB | |
| SCHEMBL4146931 | 0.67 | HPGD (0.55) | HPGDNPC1RAB9ASMN1; SMN2TP53 | |
| SCHEMBL13069099 | 0.66 | NPC1 (0.50) | HSD11B1HPGDNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4582481 | 0.65 | NPSR1 (0.36) | HSD17B10L3MBTL1CYP2A6KMT2APOLB | |
| SCHEMBL4582585 | 0.64 | GNRHR (0.37) | HPGDSMN1; SMN2LMNAL3MBTL1KMT2A | |
| SCHEMBL2872108 | 0.63 | MAOB (0.51) | HSD11B1HPGDNPC1RAB9ASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |
| EP-1972623-A1 | Arylpyridazines as fungicides | Bayer CropScience AG (DE) | 2008-09-24 | — | — | EP | disclosed |