Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDE10A | Q9Y233 | 2/20 | 0.60 |
| ▸ | CCR1 | P32246 | 4/20 | 0.53 |
| ▸ | LMNA | P02545 | 4/20 | 0.53 |
| ▸ | CCR5 | P51681 | 3/20 | 0.53 |
| ▸ | CCR8 | P51685 | 3/20 | 0.53 |
| ▸ | TSHR | P16473 | 3/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.53 |
| ▸ | MAPT | P10636 | 3/20 | 0.53 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.53 |
| ▸ | HTT | P42858 | 2/20 | 0.53 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.53 |
| ▸ | MMP2 | P08253 | 2/20 | 0.53 |
| ▸ | GMNN | O75496 | 1/20 | 0.53 |
| ▸ | TP53 | P04637 | 1/20 | 0.53 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.53 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.53 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.53 |
| ▸ | MMP9 | P14780 | 1/20 | 0.53 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.53 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL31026587 | 1.00 | PDE10A (0.60) | PDE10ACCR1LMNACCR5CCR8 | |
| SCHEMBL9528545 | 0.95 | PDE10A (0.58) | PDE10ACCR1LMNACCR5CCR8 | |
| SCHEMBL31026595 | 0.94 | PDE10A (0.57) | PDE10ACCR1LMNACCR5CCR8 | |
| Hydrochloric Acid SCHEMBL28782888 | 0.94 | PDE10A (0.57) | PDE10ACCR1LMNACCR5CCR8 | |
| SCHEMBL27915486 | 0.94 | PDE10A (0.57) | PDE10ACCR1LMNACCR5CCR8 | |
| SCHEMBL31026567 | 0.94 | PDE10A (0.57) | PDE10ACCR1LMNACCR5CCR8 | |
| SCHEMBL28813000 | 0.94 | PDE10A (0.57) | PDE10ACCR1LMNACCR5CCR8 | |
| SCHEMBL10480813 | 0.94 | PDE10A (0.57) | PDE10ACCR1LMNACCR5CCR8 | |
| SCHEMBL27971229 | 0.94 | PDE10A (0.57) | PDE10ACCR1LMNACCR5CCR8 | |
| SCHEMBL30459407 | 0.86 | CCR1 (0.54) | PDE10ACCR1CCR5KCNH2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 14 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20150125550-A1 | APPLICATION OF 2,9-DI-SEC-BUTYL-1,10-PHENANTHROLINE AS A GLIOBLASTOMA TUMOR CHEMOTHERAPY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-05-07 | — | — | US | claimed |
| US-11548792-B2 | Water-soluble gold (III) complexes, methods of producing water-soluble gold (III) complexes and their use | SZCZEPANIAK STANISLAW (PL) | 2023-01-10 | — | — | US | disclosed |
| US-20150125550-A1 | APPLICATION OF 2,9-DI-SEC-BUTYL-1,10-PHENANTHROLINE AS A GLIOBLASTOMA TUMOR CHEMOTHERAPY | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA | 2015-05-07 | — | — | US | disclosed |
| CN-103052644-A | Copper (I) complexes for optoelectronic devices | CYNORA GMBH | 2013-04-17 | — | — | CN | disclosed |
| US-20080206890-A1 | BIS(2,9-DI-TERT-BUTYL-1,10-PHENANTHROLINE)COPPER(I) COMPLEXES, METHODS OF SYNTHESIS, AND USES THEROF | WISCONSIN ALUMNI RESEARCH FOUNDATION (US) | 2008-08-28 | — | — | US | disclosed |
| US-6730788-B1 | COUPLING WITH KETONE IN PRESENCE OF LANTHANIDE II METAL COMPOUND | UNIVERSITY OF NOTRE DAME | 2004-05-04 | — | — | US | disclosed |
| EP-0227162-B1 | COMPLEX-FORMING POLYMERS | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1993-09-22 | — | — | EP | disclosed |
| US-4933455-A | Lithiated bipyridyl compounds | SHELL OIL COMPANY (US) | 1990-06-12 | — | — | US | disclosed |
| EP-0341859-A1 | Lithium ion-selective compositions, electrodes and a method of use | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-11-15 | — | — | EP | disclosed |
| EP-0339973-A1 | Substituted 1,10-phenanthrolines | EASTMAN KODAK COMPANY (a New Jersey corporation) (US) | 1989-11-02 | — | — | EP | disclosed |
| WO-1989010366-A1 | SUBSTITUTED 1,10-PHENANTHROLINES | EASTMAN KODAK COMPANY (US) | 1989-11-02 | — | — | WO | disclosed |
| US-4873212-A | Nitrogen-containing bidentate compound immobilized on a solid inorganic carrier | SHELL OIL COMPANY (US) | 1989-10-10 | — | — | US | disclosed |
| US-4873333-A | Nitrogen-containing bidentate compound immobilized on a solid inorganic carrier | SHELL OIL COMPANY (US) | 1989-10-10 | — | — | US | disclosed |
| EP-0227162-A2 | Complex-forming polymers | SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) | 1987-07-01 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080206890-A1 | BIS(2,9-DI-TERT-BUTYL-1,10-PHENANTHROLINE)COPPER(I) COMPLEXES, METHODS OF SYNTHESIS, AND USES THEROF | TTI1, TTI2, TCOF1 | PDE10A 4176/4885CCR1 2095/4885LMNA 2087/4885 |
| US-20150125550-A1 | APPLICATION OF 2,9-DI-SEC-BUTYL-1,10-PHENANTHROLINE AS A GLIOBLASTOMA TUMOR CHEMOTHERAPY | TOE1, SCLY, SUB1 | PDE10A 3550/4885CCR1 3808/4885LMNA 3356/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.