Predicted protein targets (top 2)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSD11B1 | P28845 | 19/20 | 0.45 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585111 | 0.81 | NR1H2 (0.48) | HSD11B1CHRM4 | |
| SCHEMBL4573024 | 0.77 | NR1H2 (0.42) | CHRM4 | |
| SCHEMBL6808198 | 0.76 | MAPT (0.45) | HSD11B1CHRM4 | |
| SCHEMBL6808203 | 0.76 | MAPT (0.45) | HSD11B1CHRM4 | |
| SCHEMBL9959713 | 0.75 | NOTUM (0.54) | CHRM4 | |
| SCHEMBL8109108 | 0.75 | HSD11B1 (0.49) | HSD11B1 | |
| SCHEMBL8104817 | 0.75 | HSD11B1 (0.40) | HSD11B1 | |
| SCHEMBL6811721 | 0.74 | HSD11B1 (0.42) | HSD11B1CHRM4 | |
| SCHEMBL6811731 | 0.74 | HSD11B1 (0.42) | HSD11B1CHRM4 | |
| SCHEMBL20874064 | 0.72 | MAPT (0.53) | CHRM4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2009001127-A1 | CYANOCYCLOPROPYLCARBOXAMIDES AS CATHEPSIN INHIBITORS | ASTRAZENECA AB (SE) | 2008-12-31 | — | — | WO | disclosed |