Benzoin

Benzoin

SCHEMBL458525

CC(=O)Oc1ccccc1.O=C(c1ccccc1)C(O)c1ccccc1

nearest known ligand 0.68

Full drug profile on Sugi Atlas →

Predicted protein targets (top 18)

geneUniProtsupporting neighboursconfidence
LMNA P02545 4/20 0.68
CES2 O00748 1/20 0.68
CES1 P23141 1/20 0.68
ELANE P08246 2/20 0.57
ALDH1A1 P00352 3/20 0.54
KDM4E B2RXH2 1/20 0.54
CYP3A4 P08684 1/20 0.53
MAPT P10636 3/20 0.48
TDP1 Q9NUW8 2/20 0.48
GAA P10253 2/20 0.46
HSP90AA1 P07900 1/20 0.46
L3MBTL1 Q9Y468 2/20 0.46
HPGD P15428 1/20 0.45
MAPK1 P28482 2/20 0.44
ATM Q13315 1/20 0.44
HSD17B10 Q99714 1/20 0.44
MEN1 O00255 1/20 0.43
KMT2A Q03164 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Benzoin SCHEMBL21359843 0.85 LMNA (0.75) LMNACES2CES1ELANEALDH1A1
Benzoin SCHEMBL31362056 0.85 LMNA (0.75) LMNACES2CES1ALDH1A1KDM4E
Benzoin SCHEMBL337105 0.84 LMNA (0.88) LMNACES2CES1ALDH1A1KDM4E
Benzoin SCHEMBL8865268 0.84 LMNA (0.88) LMNACES2CES1ALDH1A1KDM4E
Benzoin SCHEMBL3264348 0.84 LMNA (0.68) LMNACES2CES1ALDH1A1KDM4E
Benzoin SCHEMBL15326953 0.83 LMNA (0.72) LMNACES2CES1ALDH1A1KDM4E
Benzoin SCHEMBL23361760 0.83 LMNA (0.78) LMNACES2CES1ALDH1A1KDM4E
Benzoin SCHEMBL183095 0.83 LMNA (0.78) LMNACES2CES1ALDH1A1KDM4E
Benzoin SCHEMBL4910212 0.83 LMNA (0.84) LMNACES2CES1ALDH1A1KDM4E
Benzoin SCHEMBL9490022 0.83 LMNA (0.84) LMNACES2CES1ALDH1A1KDM4E

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4494825-A Fill port seal with first and second photosensitizers HITACHI, LTD. (JP) 1985-01-22 US claimed
EP-2613632-A1 CONTINUOUS PHOTOLYTIC PROCESS FOR THE PREPARATION OF VITAMIN D RELATED SUBSTANCES Genzyme Corporation (US) 2013-07-17 EP disclosed
US-20130172588-A1 CONTINUOUS PHOTOLYTIC PROCESS FOR THE PREPARATION OF VITAMIN D RELATED SUBSTANCES GENZYME CORPORATION (US) 2013-07-04 US disclosed
WO-2012033703-A1 CONTINUOUS PHOTOLYTIC PROCESS FOR THE PREPARATION OF VITAMIN D RELATED SUBSTANCES GENZYME CORPORATION (US) 2012-03-15 WO disclosed
US-4494825-A Fill port seal with first and second photosensitizers HITACHI, LTD. (JP) 1985-01-22 US disclosed
US-4191320-A THERMOPLASTIC RESIN, TWO AROMATIC CARBONYL SENSITIZERS OWENS-ILLINOIS, INC. (US) 1980-03-04 US disclosed
US-4056665-A Composition and process OWENS-ILLINOIS, INC. (US) 1977-11-01 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130172588-A1 CONTINUOUS PHOTOLYTIC PROCESS FOR THE PREPARATION OF VITAMIN D RELATED SUBSTANCES VDR, CYP24A1, CYP2R1 LMNA 1022/4885CES2 1932/4885CES1 3037/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.