SCHEMBL4585300

SCHEMBL4585300

OC[C@@H](O)[C@H]1OC(O)[C@@H](O)[C@H]1O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MANBA O00462 1/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
HIF1A Q16665 1/20 0.44
SLC5A2 P31639 8/20 0.35
SLC5A1 P13866 3/20 0.33
AGL P35573 1/20 0.33
OGA O60502 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15266072 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL7432236 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL15265936 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL3069911 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL9880695 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL4172279 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL15265566 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL10075956 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL22090238 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL9880689 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 192 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-4651864-A2 E3 LIGASE FAMILY FUNCTIONS AND INTERACTIONS GENENTECH, INC. (US) 2025-11-26 EP claimed
US-20250186345-A1 PHARMACEUTICAL PREPARATION OF CARBOHYDRATES FOR THERAPEUTIC USE GLYCOMINE, INC. (US) 2025-06-12 US claimed
EP-4563152-A2 PHARMACEUTICAL PREPARATION OF CARBOHYDRATES FOR THERAPEUTIC USE Glycomine, Inc. (US) 2025-06-04 EP claimed
US-12303541-B2 Erodium crassifolium L'Her plant extracts and uses thereof THE STATE OF ISRAEL, MINISTRY OF AGRICULTURE & RURAL DEVELOPMENT, AGRICULTURAL RESEARCH ORGANIZATION (ARO) (VOLCANI CENTER) (IL) 2025-05-20 US claimed
US-20250043349-A1 DEORPHANIZING ODORS USING SINGLE CELL SEQUENCING PRESIDENT AND FELLOWS OF HARVARD COLLEGE (US) 2025-02-06 US claimed
CN-119032793-A Cultivation method of artificial cordyceps sobolifera, furan type galactomannan, preparation method and application thereof 浙江省林业科学研究院 2024-11-29 CN claimed
WO-2024189607-A1 METHODS AND BIOAVAILABLE HIGHLY PERMEABLE COMPOUNDS FOR DISEASES TREATMENT DIDENKO KIRILL (MX) 2024-09-19 WO claimed
WO-2024155901-A2 E3 LIGASE FAMILY FUNCTIONS AND INTERACTIONS GENENTECH, INC. (US) 2024-07-25 WO claimed
US-20240108040-A1 HIGH INTENSITY SWEETENERS FIRMENICH INCORPORATED (US) 2024-04-04 US claimed
WO-2023195929-A2 BENCH-STABLE SULFONES AS GLYCOSYL DONORS FOR CARBOHYDRATE SYNTHESIS NATIONAL UNIVERSITY OF SINGAPORE (SG) 2023-10-12 WO claimed
EP-3347413-A1 POLYOLEFIN COMPOSITIONS SABIC Global Technologies B.V. (NL) 2018-07-18 EP claimed
WO-2017042092-A1 POLYOLEFIN COMPOSITIONS SABIC GLOBAL TECHNOLOGIES B.V. (NL) 2017-03-16 WO claimed
WO-2005092907-A2 MONOSACCHARIDE DERIVATIVES AS ANTI-CANCER AND ANTI-INFLAMMATORY AGENTS RANBAXY LABORATORIES LIMITED (IN) 2005-10-06 WO claimed
EP-1506213-A1 AN ANTIMICROBIAL AGENT GRIFFITH UNIVERSITY (AU) 2005-02-16 EP claimed
EP-1144425-B1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LAB LTD (IN) 2004-06-16 EP claimed
WO-2003097657-A1 AN ANTIMICROBIAL AGENT GRIFFITH UNIVERSITY (AU) 2003-11-27 WO claimed
US-6329344-B1 UREA DERIVATIVE OF ALKYLENE DIOXYFURAN ETHERS RANBAXY LABORATORIES LIMITED (IN) 2001-12-11 US claimed
EP-1144425-A1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES, LTD. (IN) 2001-10-17 EP claimed
WO-2000042053-A1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES LIMITED (US) 2000-07-20 WO claimed
EP-0581916-B1 ANTI-PROLIFERATIVE AND ANTI-INFLAMMATORY COMPOUNDS: 5- OR 6-DEOXY HEXOSE MONOSACCHARIDES HAVING A SATURATED NITROGEN-CONTAINING HETEROCYCLE AT THE 5- OR 6-POSITION BOUND THROUGH THE NITROGEN ATOM BOSTON LIFE SCIENCES INC (US) 1998-02-25 EP claimed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20240108040-A1 HIGH INTENSITY SWEETENERS TAS2R40, TAS2R60, TAS1R1 MANBA 1165/4885LMNA 4834/4885THRB 4014/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.