SCHEMBL4172279

SCHEMBL4172279

OC[C@H](O)[C@H]1O[C@H](O)[C@H](O)[C@@H]1O

nearest known ligand 0.44

Predicted protein targets (top 8)

geneUniProtsupporting neighboursconfidence
MANBA O00462 1/20 0.44
LMNA P02545 1/20 0.44
THRB P10828 1/20 0.44
HIF1A Q16665 1/20 0.44
SLC5A2 P31639 8/20 0.35
SLC5A1 P13866 3/20 0.33
AGL P35573 1/20 0.33
OGA O60502 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL15266072 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL7432236 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL15265936 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL4585300 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL3069911 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL9880695 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL15265566 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL10075956 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL22090238 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2
SCHEMBL9880689 1.00 MANBA (0.44) MANBALMNATHRBHIF1ASLC5A2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1144425-A1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES, LTD. (IN) 2001-10-17 EP claimed
WO-2000042053-A1 DERIVATIVES OF MONOSACCHARIDES AS CELL ADHESION INHIBITORS RANBAXY LABORATORIES LIMITED (US) 2000-07-20 WO claimed
EP-4045182-A1 MICROWAVE-ASSISTED METHOD FOR SYNTHESIS OF OLIGO- AND POLYSACCHARIDES ON SOLID PHASE Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2022-08-24 EP disclosed
EP-4045180-A1 DEVICE FOR AUTOMATED SYNTHESIS OF OLIGO- AND POLYSACCHARIDES Max-Planck-Gesellschaft zur Förderung der Wissenschaften e.V. (DE) 2022-08-24 EP disclosed
EP-2640734-A1 AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS Technion Research & Development Foundation Ltd. (IL) 2013-09-25 EP disclosed
WO-2012066546-A1 AMINOGLYCOSIDES AND USES THEREOF IN TREATING GENETIC DISORDERS TECHNION RESEARCH & DEVELOPMENT FOUNDATION LTD. (IL) 2012-05-24 WO disclosed
US-20090048186-A1 Monosaccharide Derivatives as Anti-Inflammatory and/or Anti-Cancer Agents RANBAXY LABORATORIES LIMITED (IN) 2009-02-19 US disclosed
US-20080114031-A1 MONOSACCHARIDE DERIVATIVES RANBAXY LABORATORIES LIMITED (IN) 2008-05-15 US disclosed
EP-1874788-A1 MONOSACCHARIDE DERIVATIVES AS ANTI-INFLAMMATORY AND/OR ANTI-CANCER AGENTS Ranbaxy Laboratories Limited (IN) 2008-01-09 EP disclosed
EP-1864992-A2 Monosaccharide derivatives RANBAXY LABORATORIES, LTD. (IN) 2007-12-12 EP disclosed
EP-1842855-A2 MONOSACCHARIDE DERIVATIVES AS ANTI-INFLAMMATORY AND/OR ANTI-CANCER AGENTS Ranbaxy Laboratories Limited (IN) 2007-10-10 EP disclosed
WO-2006111783-A1 MONOSACCHARIDE DERIVATIVES AS ANTI-INFLAMMATORY AND/OR ANTI-CANCER AGENTS RANBAXY LABORATORIES LIMITED (IN) 2006-10-26 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090048186-A1 Monosaccharide Derivatives as Anti-Inflammatory and/or Anti-Cancer Agents HLA-DRB1, MUC1, ASGR1 MANBA 234/4885LMNA 4860/4885THRB 2264/4885
US-20080114031-A1 MONOSACCHARIDE DERIVATIVES HLA-DRB1, MUC1, FUT5 MANBA 191/4885LMNA 4864/4885THRB 2204/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.