Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | THRB | P10828 | 4/20 | 0.53 |
| ▸ | TSHR | P16473 | 9/20 | 0.47 |
| ▸ | ALDH1A1 | P00352 | 7/20 | 0.46 |
| ▸ | TP53 | P04637 | 3/20 | 0.45 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.45 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.45 |
| ▸ | HPGD | P15428 | 1/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | POLB | P06746 | 1/20 | 0.36 |
| ▸ | APEX1 | P27695 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.36 |
| ▸ | CA1 | P00915 | 1/20 | 0.35 |
| ▸ | CA2 | P00918 | 1/20 | 0.35 |
| ▸ | KEAP1 | Q14145 | 1/20 | 0.34 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.34 |
| ▸ | HCAR2 | Q8TDS4 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Acrylic Acid Methyl Ester SCHEMBL28225099 | 0.95 | THRB (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL342856 | 0.91 | TSHR (0.55) | THRBTSHRALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL10672135 | 0.90 | THRB (0.45) | THRBTSHRALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL27647021 | 0.90 | THRB (0.72) | THRBTSHRALDH1A1TP53HIF1A | |
| SCHEMBL700688 | 0.88 | TSHR (0.59) | THRBTSHRALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL28170902 | 0.88 | THRB (0.42) | THRBTSHRALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL28016867 | 0.88 | TSHR (0.52) | THRBTSHRALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL27610783 | 0.88 | TSHR (0.49) | THRBTSHRALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL8365310 | 0.88 | TSHR (0.62) | THRBTSHRALDH1A1TP53HIF1A | |
| Acrylic Acid Methyl Ester SCHEMBL2118077 | 0.87 | THRB (0.47) | THRBTSHRALDH1A1TP53HIF1A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110024202-A | INORGANIC PARTICLES FOR NONAQUEOUS ELECTROLYTE BATTERY | 旭化成株式会社 | 2019-07-16 | — | — | CN | disclosed |
| CN-110024175-A | Nonaqueous electrolyte battery inorganic particle and the nonaqueous electrolyte battery for using it | 旭化成株式会社 | 2019-07-16 | — | — | CN | disclosed |
| EP-1385988-A4 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | SEMOREX INC (US) | 2008-04-09 | — | — | EP | disclosed |
| US-20040121405-A1 | Selective covalent-binding compounds having therapeutic diagnostic and analytical applications | SEMOREX INC. | 2004-06-24 | — | — | US | disclosed |
| EP-1385988-A2 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | Semorex Inc. (US) | 2004-02-04 | — | — | EP | disclosed |
| WO-2002083708-A2 | SELECTIVE COVALENT-BINDING COMPOUNDS HAVING THERAPEUTIC DIAGNOSTIC AND ANALYTICAL APPLICATIONS | SEMOREX INC. (US) | 2002-10-24 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040121405-A1 | Selective covalent-binding compounds having therapeutic diagnostic and analytical applications | CD2BP2, HAVCR2, EPCAM | THRB 915/4885TSHR 394/4885ALDH1A1 3296/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.