Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL342856

C=C(C)C(=O)OCCO.C=CC(=O)OC

nearest known ligand 0.55

Full drug profile on Sugi Atlas →

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
TSHR P16473 9/20 0.55
THRB P10828 2/20 0.44
ALDH1A1 P00352 7/20 0.42
HPGD P15428 1/20 0.38
TP53 P04637 3/20 0.37
HIF1A Q16665 3/20 0.37
CYP3A4 P08684 2/20 0.37
HSD17B10 Q99714 1/20 0.37
MAPK1 P28482 1/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
POLB P06746 1/20 0.34
APEX1 P27695 1/20 0.34
HTT P42858 1/20 0.34
TDP1 Q9NUW8 1/20 0.34
ACHE P22303 1/20 0.32
KEAP1 Q14145 1/20 0.31
NFE2L2 Q16236 1/20 0.31
HCAR2 Q8TDS4 1/20 0.31
CA1 P00915 1/20 0.30
CA2 P00918 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Acrylic Acid Methyl Ester SCHEMBL28016867 0.97 TSHR (0.52) TSHRTHRBALDH1A1HPGDTP53
Acrylic Acid Methyl Ester SCHEMBL10944541 0.95 TSHR (0.50) TSHRTHRBALDH1A1HPGDTP53
Acrylic Acid Ethyl Ester SCHEMBL6376428 0.92 TSHR (0.51) TSHRTHRBALDH1A1HPGDTP53
Acrylic Acid Methyl Ester SCHEMBL28138454 0.92 TSHR (0.47) TSHRTHRBALDH1A1HPGDTP53
Acrylic Acid Methyl Ester SCHEMBL4585457 0.91 THRB (0.53) TSHRTHRBALDH1A1HPGDTP53
Acrylic Acid Methyl Ester SCHEMBL28016237 0.91 TSHR (0.55) TSHRTHRBALDH1A1HPGDCYP3A4
Acrylic Acid Methyl Ester SCHEMBL27610783 0.90 TSHR (0.49) TSHRTHRBALDH1A1HPGDTP53
SCHEMBL932598 0.89 TSHR (0.70) TSHRTHRBALDH1A1HPGDTP53
Acrylic Acid Methyl Ester SCHEMBL28326447 0.89 TSHR (0.51) TSHRTHRBALDH1A1HPGDTP53
Acrylic Acid Methyl Ester SCHEMBL28174791 0.87 TSHR (0.54) TSHRTHRBALDH1A1HPGDTP53

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7794695-B2 Non-transfer cosmetic composition comprising a dispersion of particles of a silicon-free grafted ethylene polymer in a liquid fatty phase L'OREAL S.A. (FR) 2010-09-14 US claimed
US-20060134034-A1 Non-transfer cosmetic composition comprising a dispersion of a grafted ethylene polymer L'OREAL S.A. (FR) 2006-06-22 US claimed
US-20060127341-A1 Non-transfer cosmetic composition comprising a dispersion of praticles of a silicone-free grafted ethylene polymer in a liquid fatty phase L'OREAL S.A. (FR) 2006-06-15 US claimed
US-20050276779-A1 Two coat cosmetic product, its method of use and make-up kit comprising this product L'OREAL 2005-12-15 US claimed
WO-2005058274-A1 COMPOSITION COMPRISING A DISPERSION OF PARTICLES OF A GRAFTED ETHYLENIC POLYMER AND A FILM-FORMING AGENT L'ORÉAL (FR) 2005-06-30 WO claimed
CN-117585668-A Structural color carbon dot superlattice and preparation method and application thereof 广东药科大学 2024-02-23 CN disclosed
CN-114621462-B Preparation method of polyacrylate copolymerized hydrogel 南京林业大学 2023-11-10 CN disclosed
CN-114621462-A Preparation method of polyacrylate copolymerized hydrogel 南京林业大学 2022-06-14 CN disclosed
CN-109932763-A Laminated body 住友化学株式会社 2019-06-25 CN disclosed
CN-109906260-A Sealing member and method for manufacturing sealing member 井上株式会社 2019-06-18 CN disclosed
CN-109582184-A Coating composition, conductive film, touch panel and manufacturing method 麦克赛尔控股株式会社 2019-04-05 CN disclosed
CN-104416999-B Plywood 住友化学株式会社 2019-03-29 CN disclosed
US-20050276779-A1 Two coat cosmetic product, its method of use and make-up kit comprising this product L'OREAL 2005-12-15 US disclosed
US-20050220728-A1 Cosmetic composition comprising a polyglycerolated silicone elastomer KANJI MOHAMED 2005-10-06 US disclosed
EP-1579845-A2 Cosmetic composition comprising a polyglycerolated silicone elastomer L'OREAL (FR) 2005-09-28 EP disclosed
WO-2005058274-A1 COMPOSITION COMPRISING A DISPERSION OF PARTICLES OF A GRAFTED ETHYLENIC POLYMER AND A FILM-FORMING AGENT L'ORÉAL (FR) 2005-06-30 WO disclosed
US-20040156812-A1 Dispersions of polymers in organic medium, and compositions comprising them L'OREAL (FR) 2004-08-12 US disclosed
US-20020119263-A1 Radiation sensitive composition for color filters, production process therefor, color filter and color liquid crystal display element JSR CORPORATION (JP) 2002-08-29 US disclosed
CN-1213386-A Light-cured putty for repairing metal plate MINNESOTA MINING & MFG (US) 1999-04-07 CN disclosed
CN-85109215-A Can form polymkeric substance of hydrogel and its production and application 1986-09-10 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (5 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20060134034-A1 Non-transfer cosmetic composition comprising a dispersion of a grafted ethylene polymer LIPG, ETV1, ELOC TSHR 3941/4885THRB 3709/4885ALDH1A1 1416/4885
US-20060127341-A1 Non-transfer cosmetic composition comprising a dispersion of praticles of a silicone-free grafted ethylene polymer in a liquid fatty phase CUTA, PEF1, PARG TSHR 4311/4885THRB 4380/4885ALDH1A1 3291/4885
US-20040156812-A1 Dispersions of polymers in organic medium, and compositions comprising them PUF60, PDS5A, PDS5B TSHR 4328/4885THRB 4756/4885ALDH1A1 2938/4885
US-20050220728-A1 Cosmetic composition comprising a polyglycerolated silicone elastomer PLOD3, SGMS2, SGMS1 TSHR 3599/4885THRB 4181/4885ALDH1A1 1731/4885
US-20050276779-A1 Two coat cosmetic product, its method of use and make-up kit comprising this product KIT, CUTA, LIPG TSHR 4805/4885THRB 4787/4885ALDH1A1 340/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.