Acrylic Acid Methyl Ester

Acrylic Acid Methyl Ester

SCHEMBL28170902

C=C(C)C(=O)OCCNC.C=CC(=O)OC

nearest known ligand 0.42

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Predicted protein targets (top 12)

geneUniProtsupporting neighboursconfidence
THRB P10828 2/20 0.42
TSHR P16473 9/20 0.41
ALDH1A1 P00352 5/20 0.39
HPGD P15428 1/20 0.36
TP53 P04637 2/20 0.35
HIF1A Q16665 2/20 0.35
CYP3A4 P08684 1/20 0.35
HSD17B10 Q99714 1/20 0.35
POLB P06746 1/20 0.33
APEX1 P27695 1/20 0.33
HTT P42858 1/20 0.33
TDP1 Q9NUW8 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8627253 0.92 TSHR (0.44) THRBTSHRALDH1A1HPGDTP53
Acrylic Acid Methyl Ester SCHEMBL11696031 0.92 THRB (0.36) THRBTSHRALDH1A1HPGDTP53
Acrylic Acid Methyl Ester SCHEMBL4585457 0.88 THRB (0.53) THRBTSHRALDH1A1HPGDTP53
SCHEMBL108325 0.86 THRB (0.53) THRBTSHRALDH1A1POLBAPEX1
Bromide SCHEMBL7209515 0.84 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Hydrochloric Acid SCHEMBL1410288 0.84 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Ammonia Solution, Strong SCHEMBL8131325 0.84 THRB (0.52) THRBTSHRALDH1A1POLBAPEX1
Acrylic Acid Methyl Ester SCHEMBL28225099 0.83 THRB (0.49) THRBTSHRALDH1A1HPGDTP53
Acrylic Acid Methyl Ester SCHEMBL342856 0.83 TSHR (0.55) THRBTSHRALDH1A1HPGDTP53
Chloromethane SCHEMBL28216852 0.83 THRB (0.50) THRBTSHRALDH1A1POLBAPEX1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-107153335-A Electrostatic image development carrier and preparation method thereof, electrostatic charge image developer, image forming method and image forming apparatus 富士施乐株式会社 2017-09-12 CN disclosed