Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 6/20 | 0.71 |
| ▸ | MAPT | P10636 | 6/20 | 0.71 |
| ▸ | MEN1 | O00255 | 5/20 | 0.71 |
| ▸ | CYP3A4 | P08684 | 4/20 | 0.71 |
| ▸ | ALOX15 | P16050 | 3/20 | 0.71 |
| ▸ | TP53 | P04637 | 2/20 | 0.71 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.71 |
| ▸ | ESR1 | P03372 | 7/20 | 0.67 |
| ▸ | LMNA | P02545 | 7/20 | 0.67 |
| ▸ | ESR2 | Q92731 | 5/20 | 0.67 |
| ▸ | PGR | P06401 | 3/20 | 0.67 |
| ▸ | AR | P10275 | 3/20 | 0.67 |
| ▸ | HIF1A | Q16665 | 3/20 | 0.67 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.67 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.67 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.67 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.67 |
| ▸ | SHBG | P04278 | 2/20 | 0.67 |
| ▸ | SERPINA6 | P08185 | 2/20 | 0.67 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.67 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4585643 | 0.91 | LMNA (0.73) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL6331808 | 0.90 | MAPT (0.73) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL32662774 | 0.90 | MAPT (0.73) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL21540456 | 0.89 | ESR1 (0.69) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL4619351 | 0.88 | LMNA (0.62) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL7521349 | 0.87 | KMT2A (0.72) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL8177993 | 0.85 | ESR1 (0.65) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| SCHEMBL17814224 | 0.85 | ESR1 (0.77) | KMT2AMAPTMEN1CYP3A4ESR1 | |
| Estriol SCHEMBL7607646 | 0.84 | ESR1 (0.73) | KMT2AMAPTMEN1CYP3A4ALOX15 | |
| Estriol SCHEMBL5527393 | 0.84 | ESR1 (0.83) | KMT2AMAPTMEN1CYP3A4ALOX15 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20070166362-A1 | Transdermal and transmucosal preparations | KABUSHIKI KAISHA SANGI (JP) | 2007-07-19 | — | — | US | disclosed |
| EP-1797900-A1 | PREPARATION FOR PERCUTANEOUS/PERMUCOSAL ABSORPTION | KABUSHIKI KAISHA SANGI (JP) | 2007-06-20 | — | — | EP | disclosed |
| EP-1721617-A2 | Dental therapeutics containing parathyroid hormone | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2006-11-15 | — | — | EP | disclosed |
| US-6444420-B2 | NERVOUS SYSTEM DISORDERS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2002-09-03 | — | — | US | disclosed |
| US-20010016325-A1 | Activation of novel estrogen receptor supports and neuronal viability and function | BOARD OF TRUSTEE OF THE LELAND STANFORD JUNIOR UNIVERSITY, THE | 2001-08-23 | — | — | US | disclosed |
| US-6265147-B1 | DETECTING MODULATORS OF BRAIN ACTIVITY; MIX MODULATOR WITH RECEPTORS AND DETECT ACTIVATION OF RECEPTORS | THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY | 2001-07-24 | — | — | US | disclosed |
| EP-1016412-A1 | DENTAL REMEDIES CONTAINING PTH | CHUGAI SEIYAKU KABUSHIKI KAISHA (JP) | 2000-07-05 | — | — | EP | disclosed |
| EP-1016417-A1 | PRESSURE-SENSITIVE ADHESIVES FOR PERCUTANEOUS PLASTERS AND PERCUTANEOUS PLASTERS | HISAMITSU PHARMACEUTICAL CO., INC. (JP) | 2000-07-05 | — | — | EP | disclosed |
| EP-0424954-B1 | Pharmaceutical composition for treatment of osteoporosis | NIPPON ZOKI PHARMACEUTICAL CO (JP) | 1994-04-27 | — | — | EP | disclosed |
| US-5116828-A | Estrogen and thyroid hormone | NIPPON ZOKI PHARMACEUTICAL CO., LTD. (JP) | 1992-05-26 | — | — | US | disclosed |
| EP-0424954-A1 | Pharmaceutical composition for treatment of osteoporosis | NIPPON ZOKI PHARMACEUTICAL CO. LTD. (JP) | 1991-05-02 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010016325-A1 | Activation of novel estrogen receptor supports and neuronal viability and function | ESR1, GPER1, ESR2 | KMT2A 1612/4885MAPT 2499/4885MEN1 4425/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.